{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:22:06Z","timestamp":1761128526683},"reference-count":9,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2006,10,20]],"date-time":"2006-10-20T00:00:00Z","timestamp":1161302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>As a follow\u2010up to the study by Ziem <jats:italic>et al.<\/jats:italic>, in this issue, efforts to control human oesophagostomiasis and hookworm infections in northern Ghana were pursued, and the results evaluated in collaboration with the Lymphatic Filariasis Elimination Programme. This phase of evaluation of the impact of mass treatment was no longer limited to a small\u2010scale research setting: it was done both in the context of an operationally viable national control programme and as a continuation of the <jats:italic>Oesophagostomum<\/jats:italic> Intervention Research Project (OIRP). The methods of evaluation included classical stool examination with Kato thick smears, stool culture and ultrasound examination of the colon wall. The results showed that yearly population\u2010based albendazole\u2013ivermectin treatment in 11 villages scattered over north\u2010eastern Ghana, with a treatment coverage of 70\u201375%, resulted in a reduction of <jats:italic>Oesophagostomum<\/jats:italic> prevalence from about 20% pre\u2010intervention to less than 1% after 2\u2003years of mass treatment. Simultaneously, hookworm prevalence went down from 70% to approximately 15%. The data, however, cannot be readily compared with those of Ziem <jats:italic>et al.<\/jats:italic> because of the relatively crude diagnostic (single stool cultures) screening system that had to be used for the evaluation of the large\u2010scale control programme. In the research area of the OIRP, interruption of mass treatment resulted in a rising hookworm prevalence. The <jats:italic>Oesophagostomum<\/jats:italic> prevalence, on the other hand, continued to go down. Transmission of human oesophagostomiasis appears interruptible and small numbers of persistent cases of <jats:italic>Oesophagostomum<\/jats:italic> infection were shown insufficient to serve as a nucleus of renewed spread of the infection. The data suggest that both the infection with and the pathology due to human oesophagostomiasis can be eliminated and that elimination is likely to be achieved through operationally feasible albendazole\u2013ivermectin treatment as used by the Global Alliance for the Elimination of Lymphatic Filariasis.<\/jats:p>","DOI":"10.1111\/j.1365-3156.2006.01730.x","type":"journal-article","created":{"date-parts":[[2006,10,20]],"date-time":"2006-10-20T13:21:59Z","timestamp":1161350519000},"page":"1759-1763","source":"Crossref","is-referenced-by-count":6,"title":["Annual mass treatment with albendazole might eliminate human oesophagostomiasis from the endemic focus in northern Ghana"],"prefix":"10.1111","volume":"11","author":[{"given":"J. B.","family":"Ziem","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Magnussen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Horton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Spannbrucker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Yelifari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Nana Biritwum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"Polderman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,20]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"223","article-title":"Frequency of symptomatic human oesophagostomiasis (helminthoma) in northern Togo","author":"Gigase P","year":"1987","journal-title":"Helminth Zoonoses"},{"key":"e_1_2_5_3_1","first-page":"1","article-title":"High resolution DNA fingerprinting by AFLP to study the genetic variation among Oesophagostomum bifurcum (Nematoda) from human and non\u2010human primates from Ghana","volume":"129","author":"De Gruijter JM","year":"2005","journal-title":"Parasitology"},{"key":"e_1_2_5_4_1","first-page":"49","article-title":"Oesophagostomiasis in man in north Ghana","volume":"16","author":"Haaf E","year":"1964","journal-title":"Tropical and Geographical Medicine"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-4758(99)01428-3"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/321809"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2004.02.007"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2004.07.008"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2006.01729.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.trstmh.2005.11.011","article-title":"Mass treatment with albendazole reduces the prevalence and severity of Oesophagostomum\u2010induced nodular pathology in northern Ghana","volume":"100","author":"Ziem JB","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"}],"container-title":["Tropical Medicine &amp; International Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-3156.2006.01730.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-3156.2006.01730.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T01:11:55Z","timestamp":1696900315000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-3156.2006.01730.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,20]]},"references-count":9,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2006,11]]}},"alternative-id":["10.1111\/j.1365-3156.2006.01730.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-3156.2006.01730.x","archive":["Portico"],"relation":{},"ISSN":["1360-2276","1365-3156"],"issn-type":[{"value":"1360-2276","type":"print"},{"value":"1365-3156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,20]]}}}