{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T15:19:47Z","timestamp":1759159187428},"reference-count":18,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T00:00:00Z","timestamp":1160006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:bold>Objective\u2002<\/jats:bold> To determine resistance patterns of multiresistant Gram\u2010negative organisms at a surgical hospital in Ho Chi Minh City, Vietnam, in order to guide appropriate antibiotic prescribing and improve infection control procedures.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> All samples sent in for microbiological analysis over a 3\u2010month period were included. A resource neutral double disc\u2010diffusion test was introduced to detect the presence of extended\u2010spectrum <jats:italic>\u03b2<\/jats:italic>\u2010lactamase (ESBL) production.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> We obtained 350 bacterial isolates from clinical specimens; 87.4% were Gram\u2010negative bacteria (GNB). Of these, 88.9% were Enterobacteriaceae, of which 14.7% produced ESBL. Fifteen (37.5%) of these were isolated within 48\u2003h of admission. Resistance to gentamicin and ciprofloxacin occurred in 70.0% and 72.5% of those organisms that produced ESBL and in 39.5% and 38.7% of those that did not. Resistance to third\u2010generation cephalosporins was common: 36.7% of all GNB were resistant to ceftriaxone, 34.0% to cefotaxime, 19.6% to ceftazidime and 36.7% to cefoperazone.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Multiresistant Gram\u2010negative organisms are common and pose a challenge to antibiotic therapy. Successful implementation of a simple test to detect ESBL production allowed reporting of these organisms, appropriate antibiotic prescribing and infection control interventions. Development of antibiotic\u2010prescribing guidelines must take into account these resistance patterns.<\/jats:p>","DOI":"10.1111\/j.1365-3156.2006.01731.x","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T11:15:58Z","timestamp":1160046958000},"page":"1725-1730","source":"Crossref","is-referenced-by-count":8,"title":["Prevalence of multiresistant Gram\u2010negative organisms in a surgical hospital in Ho Chi Minh Cit, Vietnam"],"prefix":"10.1111","volume":"11","author":[{"given":"S. L.","family":"Jones","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. K.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. M. P.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Athan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,5]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.14.4.933-951.2001"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.12.3739-3743.2002"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2004.04.019"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(02)00458-4"},{"key":"e_1_2_5_6_1","first-page":"9","article-title":"Comparison of laboratory methods for detection of ESBL production in multi\u2010resistant Gram\u2010negative organisms","author":"Harper JJ","year":"1999","journal-title":"Australian Society of Antimicrobials Newsletter"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/10.4.867"},{"key":"e_1_2_5_8_1","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1017\/S019594170000480X","article-title":"Selected aspects of socioeconomic impact of nosocomial infections: morbidity, mortality, cost and prevention","volume":"17","author":"Jarvis WR","year":"1996","journal-title":"Infection Control and Hospital Epidemiology"},{"key":"e_1_2_5_9_1","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1128\/jcm.32.3.691-696.1994","article-title":"Detection of Klebsiella pneumoniae and Escherichia coli strains producing extended spectrum beta\u2010lactamases","volume":"32","author":"Katsanis GP","year":"1994","journal-title":"Journal of Clinical Microbiology"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.8.4.557"},{"key":"e_1_2_5_11_1","first-page":"25","article-title":"Antibiotic resistance conferred by extended\u2010spectrum beta\u2010lactamases: origin, detection, epidemiology and clinical implications","volume":"24","author":"Monaghan WM","year":"2004","journal-title":"Australian Journal of Medical Science"},{"key":"e_1_2_5_12_1","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing. Twelfth Informational Supplement. Approved Standard M7\u2010A2","author":"National Committee for Clinical Laboratory Standards","year":"2002"},{"key":"e_1_2_5_13_1","author":"Nguyen THT","year":"2004","journal-title":"Globalisation and its Effects on Health Care and Occupational Health in Vietnam"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0277-9536(01)00155-1"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.280.14.1233"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.1.118"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1086\/502070"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3156.1997.d01-213.x"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0403.980320"}],"container-title":["Tropical Medicine &amp; International Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-3156.2006.01731.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-3156.2006.01731.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T01:12:05Z","timestamp":1696900325000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-3156.2006.01731.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,5]]},"references-count":18,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2006,11]]}},"alternative-id":["10.1111\/j.1365-3156.2006.01731.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-3156.2006.01731.x","archive":["Portico"],"relation":{},"ISSN":["1360-2276","1365-3156"],"issn-type":[{"value":"1360-2276","type":"print"},{"value":"1365-3156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,5]]}}}