{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:52:45Z","timestamp":1791197565587,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2007,10,23]],"date-time":"2007-10-23T00:00:00Z","timestamp":1193097600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2007,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:bold>Objective\u2002<\/jats:bold> To determine the burden of congenital malaria in newborns in Nigeria.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> In a prospective multi\u2010centre study, 1875 consecutive mother\u2013baby pairs were enrolled over a continuous 12\u2010month period. Blood smears were prepared from mothers, neonates, placental aspirates and cord blood within 4\u2003h of delivery. Outcome variables were patent parasitaemia in the mother, placenta, cord and neonate in addition to maternal and neonatal haematocrit.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Patent parasitaemia was detected in 95 neonates (5.1%). The occurrence varied between study centres, but was found year round in all sites. The mean parasite density among infected neonates was low (48 asexual forms per \u03bcl, range 8\u2013200\/\u03bcl). Maternal and placental parasitaemia were the most important risk factors for patent neonatal parasitaemia (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.0001). Spontaneous clearance of parasitaemia occurred in 62.1% of neonates before day 2. 33.7% were symptomatic within 3\u2003days of birth.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Congenital malaria is often asymptomatic, clears spontaneously and may not warrant treatment. However, newborns with unexplained fever and refusal to feed in malaria endemic areas should be tested for malaria.<\/jats:p>","DOI":"10.1111\/j.1365-3156.2007.01931.x","type":"journal-article","created":{"date-parts":[[2010,8,11]],"date-time":"2010-08-11T21:36:38Z","timestamp":1281562598000},"page":"1279-1287","source":"Crossref","is-referenced-by-count":82,"title":["Epidemiology of congenital malaria in Nigeria: a multi\u2010centre study"],"prefix":"10.1111","volume":"12","author":[{"given":"Catherine","family":"Falade","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olugbenga","family":"Mokuolu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrietta","family":"Okafor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adeola","family":"Orogade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adegoke","family":"Falade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olanrewaju","family":"Adedoyin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tagbo","family":"Oguonu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maman","family":"Aisha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davidson H.","family":"Hamer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael V.","family":"Callahan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,10,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)82056-6"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/00034983.1952.11685522"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2004.01307.x"},{"issue":"2","key":"e_1_2_7_5_1","first-page":"77","article-title":"Transplacental passage of Plasmodium falciparum and seroevaluation of newborns in Northern Nigeria","volume":"27","author":"Egwunyenga OA","year":"1995","journal-title":"Journal of Communicable Diseases"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200303070-00015"},{"key":"e_1_2_7_7_1","volume-title":"Technical report on the 2003 National HIV\/Syphilis Sentinel Survey among pregnant women attending antenatal clinics in Nigeria","author":"Federal Ministry of Health","year":"2004"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/000992289703600706"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/41.6.330"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(02)90284-1"},{"issue":"4","key":"e_1_2_7_11_1","first-page":"213","article-title":"A study of malaria parasitaemia in pregnant women, placentae, cord blood and neonates born in Lagos Nigeria","volume":"12","author":"Lamikanra OT","year":"1993","journal-title":"West African Journal of Medicine"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4799.1382"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(83)90081-0"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(01)90141-5"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmi044"},{"key":"e_1_2_7_16_1","article-title":"Effect of anti\u2010malarial chemoprophylaxis and anti\u2010vector preventive measures during pregnancy on the incidence of placental and congenital malaria in Nigeria","volume":"77","author":"Okafor HU","year":"2006","journal-title":"Supplement to the American Journal of Tropical Medicine and Hygiene"},{"key":"e_1_2_7_17_1","first-page":"211","article-title":"Congenital malaria in Nigeria: a revisit","volume":"29","author":"Olowu JA","year":"2000","journal-title":"African Journal of Medicine and Medical Sciences"},{"issue":"4","key":"e_1_2_7_18_1","first-page":"587","article-title":"Differences in blood status of three ethnic groups inhabiting the same locality in Northern Nigeria. 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