{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:28:59Z","timestamp":1762079339415},"reference-count":41,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,5,11]],"date-time":"2012-05-11T00:00:00Z","timestamp":1336694400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objective\u2002<\/jats:bold> To assess individual compliance with annual ivermectin treatment in onchocerciasis\u2010endemic villages.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Multi\u2010site study in eight APOC\u2010sponsored projects in Cameroon, Nigeria and Uganda to identify the socio\u2010demographic correlates of compliance with ivermectin treatment. A structured questionnaire was administered on 2305 persons aged 10\u2003years and above. Two categories of respondents were purposively selected to obtain both high and low compliers: people who took ivermectin 6\u20138 times and 0\u20132 times previously. Simple descriptive statistics were employed in characterizing the respondents into high and low compliers, while some socio\u2010demographic and key perceptual factors were employed in regression models constructed to explain levels of compliance among the respondents.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Some demographic and perceptual factors associated with compliance were identified. Compliance was more common among men (54.4%) (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.001). Adults (54.6%) had greater rates of high compliance (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.001. The mean age of high compliers (41.5\u2003years) was significantly older (35.8\u2003years) (<jats:italic>t<\/jats:italic>\u2003=\u20038.46, <jats:italic>P<\/jats:italic>\u2003&lt;\u20030.001). Perception of onchocerciasis and effectiveness of ivermectin influenced compliance. 81.4% of respondents saw benefits in annual ivermectin treatment, high compliance among those who saw benefits was 59.3% compared to 13.3% of those who did not (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.001).<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Efforts to increase compliance with ivermectin treatment should focus on providing health education to youth and women. Health education should also highlight the benefits of taking ivermectin.<\/jats:p>","DOI":"10.1111\/j.1365-3156.2012.03007.x","type":"journal-article","created":{"date-parts":[[2012,5,11]],"date-time":"2012-05-11T11:06:22Z","timestamp":1336734382000},"page":"920-930","source":"Crossref","is-referenced-by-count":33,"title":["Characteristics of persons who complied with and failed to comply with annual ivermectin treatment"],"prefix":"10.1111","volume":"17","author":[{"given":"William R.","family":"Brieger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph C.","family":"Okeibunor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adenike O.","family":"Abiose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Ndyomugyenyi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Wanji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Elhassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uche V.","family":"Amazigo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,5,11]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"African Programme for Onchocerciasis Control(2004)Year 2004 progress report of WHO\/APOC.http:\/\/www.apoc.bf\/en\/download.htm."},{"key":"e_1_2_5_3_1","unstructured":"African Programme for Onchocerciasis Control(2005)Report of the 20th session of the Technical Consultative Committee (TCC) Ouagadougou 14\u201319 March 2005.http:\/\/www.apoc.bf\/en\/download.htm."},{"key":"e_1_2_5_4_1","unstructured":"African Programme for Onchocerciasis Control(2006)Special meeting on sustainability of CDTI: final communiqu\u00e9 and recommendations Ouagadougou 2\u20135 February 2006.http:\/\/www.apoc.bf\/en\/download.htm."},{"key":"e_1_2_5_5_1","unstructured":"African Programme for Onchocerciasis Control(2007)Community Directed Treatment with Ivermectin (CDTI): a pratical guide for trainers of Community Directed Distributors (CDDs).http:\/\/www.apoc.bf\/en\/CDTI."},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0277-9536(99)00336-6"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69786-9"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2007.01.018"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1049-3867(02)00132-9"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2883-2-8"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/004947558601600104"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3156.1997.d01-123.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3156.2002.00826.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2006.01796.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.2190\/VKHL-JXC5-WK91-8QGQ"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0b013e318032937e"},{"key":"e_1_2_5_17_1","doi-asserted-by":"crossref","first-page":"556","DOI":"10.4269\/ajtmh.2004.70.556","article-title":"A longitudinal study of impact of repeated mass ivermectin treatment on clinical manifestations of onchocerciasis in Imo State, Nigeria","volume":"70","author":"Emukah EC","year":"2004","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1348\/135910704773891050"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0361-090X(03)00133-8"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2883-2-S1-S10"},{"key":"e_1_2_5_21_1","first-page":"290","article-title":"Compliance to antiretroviral therapy among AIDS patients in Aminu Kano Teaching Hospital, Kano, Nigeria","volume":"14","author":"Iliyasu Z","year":"2005","journal-title":"Niger Journal of Medicine"},{"key":"e_1_2_5_22_1","unstructured":"IPSOR Medication Compliance and Persistence Special Interest Group(2006)Standardizing definition of terms. 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