{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T17:58:13Z","timestamp":1723053493455},"reference-count":12,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2012,10,29]],"date-time":"2012-10-29T00:00:00Z","timestamp":1351468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objective\u2002<\/jats:bold> To present an effective classification method based on the prevalence of <jats:italic>Schistosoma mansoni<\/jats:italic> in the community.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> We created decision rules (defined by cut\u2010offs for number of positive slides), which account for imperfect sensitivity, both with a simple adjustment of fixed sensitivity and with a more complex adjustment of changing sensitivity with prevalence. To reduce screening costs while maintaining accuracy, we propose a <jats:italic>pooled<\/jats:italic> classification method. To estimate sensitivity, we use the De Vlas model for worm and egg distributions. We compare the proposed method with the standard method to investigate differences in efficiency, measured by number of slides read, and accuracy, measured by probability of correct classification.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Modelling varying sensitivity lowers the lower cut\u2010off more significantly than the upper cut\u2010off, correctly classifying regions as moderate rather than lower, thus receiving life\u2010saving treatment. The classification method goes directly to classification on the basis of positive pools, avoiding having to know sensitivity to estimate prevalence. For model parameter values describing worm and egg distributions among children, the <jats:italic>pooled<\/jats:italic> method with <jats:italic>25 slides<\/jats:italic> achieves an expected 89.9% probability of correct classification, whereas the standard method with <jats:italic>50 slides<\/jats:italic> achieves 88.7%.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Among children, it is more efficient and more accurate to use the pooled method for classification of <jats:italic>S.\u00a0mansoni<\/jats:italic> prevalence than the current standard method.<\/jats:p>","DOI":"10.1111\/j.1365-3156.2012.03098.x","type":"journal-article","created":{"date-parts":[[2012,10,30]],"date-time":"2012-10-30T01:27:41Z","timestamp":1351560461000},"page":"1470-1477","source":"Crossref","is-referenced-by-count":0,"title":["Effective classification of the prevalence of <i>Schistosoma mansoni<\/i>"],"prefix":"10.1111","volume":"17","author":[{"given":"Shira A.","family":"Mitchell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello","family":"Pagano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,10,29]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Preventive Chemotherapy in Human Helminthiasis","author":"Albonico M","year":"2006"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2005.01446.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2006.01594.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000431"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(92)90144-Q"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/S003118200006371X"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(93)90132-Y"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3156.2003.01176.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2012.12-0216"},{"key":"e_1_2_6_11_1","unstructured":"MontresorA CromptonDWT BundyDAP HallA&SavioliL(1998).Guidelines for the evaluation of soil\u2010transmitted helminthiasis and schistosomiasis at the community level. whqlibdoc.who.int\/hq\/1998\/WHO_CTD_SIP_98.1.pdf."},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742-7622-7-3"},{"key":"e_1_2_6_13_1","doi-asserted-by":"crossref","first-page":"561","DOI":"10.4269\/ajtmh.1990.42.561","article-title":"Human schistosomiasis in Cameroon. 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