{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T16:04:47Z","timestamp":1773417887396,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,3,3]],"date-time":"2006-03-03T00:00:00Z","timestamp":1141344000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Clinical, cytological, microbial and histopathological features of feline acne were investigated in 22 cats referred or volunteered to a veterinary dermatology practice in the south\u2010west region of the USA. For comparison, same parameters were evaluated in five unaffected pet cats. Additionally, all cats were evaluated by immunohistochemistry (IHC) for the presence of feline calicivirus (FCV) and feline herpes virus (FHV\u20101) in acne lesions. The age of onset of acne in affected cats ranged from 6\u00a0months to 14\u00a0years with a median of 4\u00a0years. The most common dermatologic lesions were comedones (73%), alopecia (68%), crusts (55%), papules (45%) and erythema (41%). Pruritus was reported in 35% of the affected cats. Cytological evidence of<jats:italic>Malassezia pachydermatitis<\/jats:italic>was present on 4\/22 (18%) of affected cats.<jats:italic>Microsporum canis<\/jats:italic>was isolated from a single affected cat. Bacteria were isolated from 10 of the 22 (45%) affected cats; coagulase\u2010positive staphylococci and alpha\u2010haemolytic streptococci were most common. Histopathological features included lymphoplasmacytic periductal inflammation (86%), sebaceous gland duct dilatation (73%), follicular keratosis with plugging and dilatation (59%), epitrichial gland occlusion and dilatation (32%), folliculitis (27%), pyogranulomatous sebaceous adenitis (23%) and furunculosis (23%). In one affected cat from a household with five cats, simultaneously having feline acne, FCV antigen was detected in the biopsy of the chin by IHC. Chin tissue samples from all other affected cats, as well as the five healthy cats, were negative by IHC for FCV and FHV\u20101 antigens.<\/jats:p>","DOI":"10.1111\/j.1365-3164.2006.00507.x","type":"journal-article","created":{"date-parts":[[2006,3,3]],"date-time":"2006-03-03T15:00:06Z","timestamp":1141398006000},"page":"134-140","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["An evaluation of the clinical, cytological, infectious and histopathological features of feline acne"],"prefix":"10.1111","volume":"17","author":[{"given":"E.","family":"Jazic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. S.","family":"Coyner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. G.","family":"Loeffler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. P.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,3,3]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"crossref","unstructured":"ScottDW MillerWH GriffinCE.Keratinization defects.Muller and Kirk's Small Animal Dermatology 6th edn. Philadelphia:W.B. Saunders 2001:1042\u20133.","DOI":"10.1016\/B978-0-7216-7618-0.50018-3"},{"key":"e_1_2_6_3_2","first-page":"230","volume-title":"The Veterinary Annual","author":"Bond R","year":"1993"},{"key":"e_1_2_6_4_2","first-page":"504","article-title":"The Pathogenesis, diagnosis, and management of feline acne","volume":"5","author":"Rosenkrantz WS","year":"1991","journal-title":"Veterinary Medicine"},{"key":"e_1_2_6_5_2","first-page":"331","article-title":"Feline dermatology 1900\u201378: a monograph","volume":"16","author":"Scott DW","year":"1980","journal-title":"Journal of American Animal Hospital Association"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3164.1997.d01-16.x"},{"key":"e_1_2_6_7_2","first-page":"258","volume-title":"Veterinary Dermatopathology","author":"Gross TL","year":"1992"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/svms.2001.27597"},{"key":"e_1_2_6_9_2","first-page":"1197","article-title":"Clinical update on feline dermatophytosis \u2013 Part I","volume":"17","author":"DeBoer DJ","year":"1995","journal-title":"Compendium on Continuing Education for the Practicing Veterinarian"},{"key":"e_1_2_6_10_2","unstructured":"MasonKVet al.Malassezia pachydermatisassociated dermatitis in the cat.Proceedings of the American Academy of Veterinary Dermatology and American College of Veterinary Dermatology Annual Meeting.Charleston South Carolina 1994:83."},{"key":"e_1_2_6_11_2","first-page":"331","article-title":"Feline dermatology 1900\u201380: a monograph","volume":"16","author":"Scott DW","year":"1980","journal-title":"Journal of the American Animal Hospital Association"},{"key":"e_1_2_6_12_2","first-page":"1824","article-title":"Distribution of staphylococcal species on clinically healthy cats","volume":"46","author":"Cox HU","year":"1985","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1135(84)90045-2"},{"key":"e_1_2_6_14_2","first-page":"1080","article-title":"Frequency and antimicrobial susceptibility of Staphylococcus spp. isolated from feline skin lesions","volume":"193","author":"Medleaua L","year":"1988","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_6_15_2","doi-asserted-by":"crossref","first-page":"502","DOI":"10.2460\/javma.1999.214.04.502","article-title":"Evaluation of serologic and viral detection methods for diagnosing feline herpesvirus\u20101 infection in cats with acute respiratory tract or chronic ocular disease","volume":"214","author":"Maggs DJ","year":"1999","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_6_16_2","first-page":"166","article-title":"Feline upper respiratory tract pathogens: herpesvirus\u20101 and calicivirus","volume":"23","author":"Sykes JE","year":"2001","journal-title":"Compendium on Continuing Education for the Practicing Veterinarian"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(99)50126-5"},{"key":"e_1_2_6_18_2","volume-title":"Textbook of Veterinary International Medicine","author":"Pedersen NC","year":"1983"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(03)00025-1"}],"container-title":["Veterinary Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-3164.2006.00507.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-3164.2006.00507.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,3]],"date-time":"2024-02-03T05:30:35Z","timestamp":1706938235000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-3164.2006.00507.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3,3]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["10.1111\/j.1365-3164.2006.00507.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-3164.2006.00507.x","archive":["Portico"],"relation":{},"ISSN":["0959-4493","1365-3164"],"issn-type":[{"value":"0959-4493","type":"print"},{"value":"1365-3164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,3,3]]},"assertion":[{"value":"2006-03-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}