{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T01:44:36Z","timestamp":1789868676625,"version":"4.0.1"},"reference-count":47,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,2,24]],"date-time":"2012-02-24T00:00:00Z","timestamp":1330041600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:p><jats:bold>Background\u2002\u2013\u2002<\/jats:bold> Meticillin\u2010resistant staphylococci are significant pathogens in veterinary dermatology, yet longitudinal studies of the impact of routine antimicrobial therapy on emergence or resolution of resistance are lacking.<\/jats:p><jats:p><jats:bold>Objectives\u2002\u2013\u2002<\/jats:bold> To determine the prevalence of meticillin\u2010resistant staphylococci on skin and carriage sites in dogs with bacterial pyoderma and evaluate the prevalence of meticillin\u2010resistant <jats:italic>Staphylococcus pseudintermedius<\/jats:italic> (MRSP) colonization after successful treatment of pyoderma.<\/jats:p><jats:p><jats:bold>Animals\u2002\u2013\u2002<\/jats:bold> One hundred and seventy\u2010three dogs that presented to a dermatology referral service with pyoderma and 41 healthy control dogs.<\/jats:p><jats:p><jats:bold>Methods\u2002\u2013\u2002<\/jats:bold> Skin, nasal and rectal swabs for bacterial culture were collected at the time of referral and after clinical resolution of the pyoderma. Meticillin resistance was confirmed by demonstration of penicillin binding protein 2a antigen.<\/jats:p><jats:p><jats:bold>Results\u2002\u2013\u2002<\/jats:bold> Initially, skin cultures yielded MRSP in 70 (40.5%) dogs, meticillin\u2010resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (MRSA) in three (1.7%) and meticillin\u2010resistant <jats:italic>Staphylococcus schleiferi<\/jats:italic> ssp. <jats:italic>coagulans<\/jats:italic> (MRSScoag) in five (2.9%). Samples collected from the nose and rectum (carriage sites) yielded MRSP in 59 (34.1%) dogs, MRSA in 11 (6.4%) and MRSScoag in seven (4.0%). One hundred and two dogs were available for follow\u2010up cultures after clinical cure. Of 42 dogs initially diagnosed with MRSP pyoderma, MRSP was isolated at follow\u2010up from skin in 19 (45.2%) and carriage sites in 20 (47.6%). Of 60 dogs that did not have MRSP pyoderma initially, MRSP was isolated post\u2010treatment from the skin in 17 (28.3%), and MRSP from carriage sites increased from 7.8% (initially) to 26.7% (<jats:italic>P<\/jats:italic>\u2003=\u20030.0022).<\/jats:p><jats:p><jats:bold>Conclusions and clinical importance\u2002\u2013\u2002<\/jats:bold> Colonization by MRSP often persists after resolution of MRSP pyoderma. Acquisition of MRSP during treatment appears to be common.<\/jats:p>","DOI":"10.1111\/j.1365-3164.2012.01035.x","type":"journal-article","created":{"date-parts":[[2012,2,24]],"date-time":"2012-02-24T19:06:34Z","timestamp":1330110394000},"page":"369","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":101,"title":["Prevalence of meticillin\u2010resistant <i>Staphylococcus pseudintermedius<\/i> (MRSP) from skin and carriage sites of dogs after treatment of their meticillin\u2010resistant or meticillin\u2010sensitive staphylococcal pyoderma"],"prefix":"10.1111","volume":"23","author":[{"given":"Karri M.","family":"Beck","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen E.","family":"Waisglass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hani L. 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