{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T22:37:31Z","timestamp":1782945451697,"version":"3.54.5"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2004,4,29]],"date-time":"2004-04-29T00:00:00Z","timestamp":1083196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2004,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> The role of psychological factors in the pathogenesis of alopecia areata (AA) has long been the subject of debate. Numerous studies have provided controversial results.<\/jats:p><jats:p><jats:bold>Aim\u2002<\/jats:bold> This case\u2013control study was undertaken to determine the significance of stressful life events and other psychological factors in the etiopathogenesis of AA. The impact of the disease on the quality of life was also assessed.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Fifty\u2010two adult patients (18 females and 34 males) diagnosed with AA and 52 age\u2010 and sex\u2010matched individuals selected from hospital staff without any hair loss (control group) were evaluated using the major life events scale, Beck depression and Beck anxiety inventories, and the Short Form\u201036 health survey (SF\u201036). In addition, comparison was performed between two patient groups created according to whether or not they linked emotional trauma with their AA attack.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> There was no statistically significant difference between the patient and control groups with regard to the total scores of stressful major life events, depression, and anxiety. Of the eight subscales on SF\u201036, vitality and mental health scores were higher in the control group, whereas social functioning scores were higher in the patients. The total number of stressful life events was higher in patients who attributed their disease to a stressful life event than in those who did not.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> It appears unlikely that anxiety and depression play a major role in the etiopathogenesis of AA, but stressful life events may act as a trigger in the onset and\/or exacerbation of the disease. Furthermore, AA seems to have a partly negative impact on the health\u2010related quality of life.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2004.02028.x","type":"journal-article","created":{"date-parts":[[2004,4,29]],"date-time":"2004-04-29T12:34:04Z","timestamp":1083242044000},"page":"352-356","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":103,"title":["The role of psychological factors in alopecia areata and the impact of the disease on the quality of life"],"prefix":"10.1111","volume":"43","author":[{"given":"A. T\u00fclin","family":"G\u00fcle\u00e7","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilg\u00fcn","family":"Tanr\u0131verdi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c7a\u011fay","family":"D\u00fcr\u00fc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasemin","family":"Saray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cenk","family":"Ak\u00e7al\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,4,29]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1999.tb02063.x"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(05)70394-6"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(18)30280-8"},{"key":"e_1_2_5_5_2","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1001\/jama.1995.03520420031025","article-title":"Alopecia areata and presence of cytomegalovirus DNA","volume":"273","author":"Skinner RB","year":"1995","journal-title":"J Am Med Assoc"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1955.03730350056010"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1958.tb13304.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1963.01590210048007"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70195-7"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1961.01710120031004"},{"key":"e_1_2_5_11_2","volume-title":"Cognitive Therapy for Depression.","author":"Beck AT","year":"1979"},{"key":"e_1_2_5_12_2","first-page":"118","article-title":"A study on the validity of Beck depression inventory","volume":"6","author":"Hisli N","year":"1988","journal-title":"J Psychol (Psikoloji Dergisi)"},{"key":"e_1_2_5_13_2","first-page":"3","article-title":"Validity and reliability of Beck depression inventory in university students","volume":"7","author":"Hisli N","year":"1989","journal-title":"J Psychol (Psikoloji Dergisi)"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.56.6.893"},{"key":"e_1_2_5_15_2","volume-title":"J Cog Psychother","author":"Ulsoy M","year":"1998"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199206000-00002"},{"key":"e_1_2_5_17_2","first-page":"102","article-title":"Validity and reliability of Turkish version of SF\u201036","volume":"12","author":"Ko\u00e7yi\u011fit H","year":"1999","journal-title":"J Drug Ther (\u0130la\u00e7 ve Tedavi Dergisi)"},{"key":"e_1_2_5_18_2","unstructured":"SoriasS.Research of the effects of stressful life events on patients and controls (in Turkish).Thesis.Izmir: Ege University School of Medicine1982."},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4691.1250"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5176.846"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1159\/000287786"},{"key":"e_1_2_5_22_2","doi-asserted-by":"crossref","first-page":"296","DOI":"10.2340\/0001555577296298","article-title":"Stress and alopecia areata: a psychodermatologic study","volume":"77","author":"Gupta MA","year":"1997","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"e_1_2_5_23_2","doi-asserted-by":"crossref","first-page":"279","DOI":"10.2340\/0001555572279280","article-title":"Can alopecia areata be triggered by emotional stress?","volume":"72","author":"Van der Steen P","year":"1992","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0010-440X(91)90045-E"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1994.tb01018.x"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-4632.2004.02028.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-4632.2004.02028.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T21:56:58Z","timestamp":1696888618000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-4632.2004.02028.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,4,29]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,5]]}},"alternative-id":["10.1111\/j.1365-4632.2004.02028.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-4632.2004.02028.x","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,4,29]]},"assertion":[{"value":"2004-04-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}