{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T19:09:27Z","timestamp":1767899367950,"version":"3.49.0"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2004,7,22]],"date-time":"2004-07-22T00:00:00Z","timestamp":1090454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2005,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Recently, it has been shown that UVB phototherapy may be more effective than UVA in the treatment of vitiligo. Currently, however, no studies have compared the efficacy of UVB<jats:sub>311\u00a0nm<\/jats:sub> and broad\u2010band UVB therapy. Calcipotriol has recently been reported to be effective adjunctive treatment for vitiligo, enhancing the efficacy of 8\u2010methoxypsoralen plus UVA (PUVA) therapy.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Ten patients were enrolled in the study; nine completed the 12\u00a0months of therapy. The upper part of the body was treated twice weekly with UVB<jats:sub>311\u00a0nm<\/jats:sub> and the lower part with broad\u2010band UVB. Calcipotriol was applied onto the vitiligo lesions of the right side of the body and placebo on the left side. Repigmentation was documented by photography, planimetry, and Vitiligo Disease Activity (VIDA) score. The quality of life was measured by the Dermatology Life Quality Index (DLQI).<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> After 7\u201316\u00a0weeks, six of the nine patients showed initial repigmentation on the side treated with UVB<jats:sub>311\u00a0nm<\/jats:sub>. After 6\u00a0months of treatment, none of the patients showed repigmentation on the areas treated with broad\u2010band UVB, which prompted us to apply UVB<jats:sub>311\u00a0nm<\/jats:sub> all over the body. At the end of 12\u00a0months, two patients showed &gt;\u00a075% repigmentation, two showed 51\u201375%, two showed 26\u201350%, and three showed 0\u201325%. In all patients with progressive vitiligo (seven of the nine patients), disease activity was stopped. Remarkably, vitiligo lesions treated with calcipotriol initially showed delayed repigmentation compared with control areas; however, there was no therapeutic difference between calcipotriol and placebo, both in combination with UVB<jats:sub>311\u00a0nm<\/jats:sub>, by the end of the study. The DLQI score improved significantly by an average of 28%.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> UVB<jats:sub>311\u00a0nm<\/jats:sub> therapy was effective in the treatment of vitiligo, whereas broad\u2010band UVB had no effect. Combination with calcipotriol ointment was not superior to UVB<jats:sub>311\u00a0nm<\/jats:sub> monotherapy. The quality of life significantly improved with narrow\u2010band UVB<jats:sub>311\u00a0nm<\/jats:sub> phototherapy.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2004.02154.x","type":"journal-article","created":{"date-parts":[[2005,8,26]],"date-time":"2005-08-26T08:23:10Z","timestamp":1125044590000},"page":"736-742","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":64,"title":["Narrow\u2010band UVB<sub>311\u00a0nm<\/sub> vs. broad\u2010band UVB therapy in combination with topical calcipotriol vs. placebo in 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