{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T17:24:43Z","timestamp":1774891483662,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,5,20]],"date-time":"2004-05-20T00:00:00Z","timestamp":1085011200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Facial appearance plays a large role in self\u2010perception and interaction with others. Visible facial skin lesions are a common condition.<\/jats:p><jats:p><jats:bold>Purpose\u2002<\/jats:bold> This study assessed factors associated with health\u2010related quality of life (HRQOL) in women with visible facial skin lesions.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> The study included 73 women with one or more of the following conditions: acne, dermatosis papulosis, hypopigmentation, lentigenes, melasma, rosacea, vascular proliferations and other facial scars. The Skindex\u201016 was used as a measure of HRQOL. Fear of negative evaluation (FNE) was assessed to determine whether self\u2010perception characteristics relate to HRQOL.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> There were strong correlations in both bivariate and multivariate analyses among increased FNE, heightened perception of QOL without the facial condition and lower overall HRQOL (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05 and <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01, respectively). There were no differences in HRQOL by type of facial condition, as well as no effects of the area covered by the condition on HRQOL. Interestingly, women not using foundations represented only 10% of the study population and had better HRQOL than women who did use foundations.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Severe facial blemishes of any cause have a significant impact on women's QOL, and the effect of these lesions is mediated in part by psychological characteristics related to self\u2010perception and self\u2010presentation.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2004.02371.x","type":"journal-article","created":{"date-parts":[[2006,1,20]],"date-time":"2006-01-20T17:31:58Z","timestamp":1137778318000},"page":"111-115","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":69,"title":["Correlates of health\u2010related quality of life in women with severe facial blemishes"],"prefix":"10.1111","volume":"45","author":[{"given":"Rajesh","family":"Balkrishnan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy J.","family":"McMichael","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judy Y.","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian T.","family":"Camacho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine R.","family":"Shew","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Bouloc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen R.","family":"Rapp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven R.","family":"Feldman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,5,20]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"439","article-title":"Corrective cosmetics: need, evaluation and use","volume":"41","author":"Roberts NC","year":"1988","journal-title":"Cutis"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900040210"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1989.tb01800.x"},{"key":"e_1_2_6_5_2","first-page":"274","article-title":"The stigma of port wine stains","volume":"45","author":"Lanigan S","year":"1991","journal-title":"Br J Hospital Med"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(86)70160-6"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1978.01640210075025"},{"key":"e_1_2_6_8_2","first-page":"493","article-title":"Response to cosmetic disfigurement: patients with vitiligo","volume":"39","author":"Porter J","year":"1987","journal-title":"Cutis"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(90)70028-G"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(97)70210-X"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1997.5541510.x"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/120347540100500202"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12365600"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb01167.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1994.01690060057005"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.17.6.530"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04444.x"},{"key":"e_1_2_6_18_2","volume-title":"Econometric Analysis","author":"Greene WH","year":"1998"},{"key":"e_1_2_6_19_2","unstructured":"STATA Statistical Software.Release 5.0. 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