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Eleven patients met the inclusion criteria.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Ten patients (91%) had positive patch tests to metals. In eight (73%), the oral cancer was adjacent to a dental restoration containing a metal to which the patient was allergic. Prevalence of gold, mercury, silver, and copper allergy among these patients was substantially higher than that reported in the available worldwide patch\u2010test clinic population.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Contact allergy to metal dental restorations may be a risk factor for development of intraoral squamous cell carcinoma.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2004.02417.x","type":"journal-article","created":{"date-parts":[[2006,2,27]],"date-time":"2006-02-27T16:42:58Z","timestamp":1141058578000},"page":"265-271","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Oral metal contact allergy: a pilot study on the cause of oral squamous cell carcinoma"],"prefix":"10.1111","volume":"45","author":[{"given":"Firas G.","family":"Hougeir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James 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