{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:52:45Z","timestamp":1764996765098},"reference-count":12,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2004,7,22]],"date-time":"2004-07-22T00:00:00Z","timestamp":1090454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2005,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Basidiobolomycosis is a rare chronic subcutaneous infection caused by <jats:italic>Basidiobolus ranarum<\/jats:italic>, which is usually treated with potassium iodide. Extensive deforming lesions in children can occur owing to lack of early diagnosis and\/or inappropriate treatment.<\/jats:p><jats:p><jats:bold>Case report\u2002<\/jats:bold> An 8\u2010year\u2010old girl child presented to us with extensive deforming plaque\u2010like lesions over the left thigh and leg with multiple ulcerations of 1\u00a0year's duration. Histopathology was suggestive of subcutaneous zygomycosis with Splendore Hoeppli phenomenon. Microscopic examination of the tissue showed branching, sparsely septate fungal hyphae on a 10%KOH mount, and culture yielded <jats:italic>Basidiobolus ranarum<\/jats:italic>. The patient was initially treated with potassium iodide for 6\u00a0weeks to which only a poor response was observed. Itraconazole therapy resulted in rapid regression of the lesions and complete resolution after 15\u00a0weeks of therapy. She continues to be disease\u2010free at 1\u00a0year of follow up.<\/jats:p><jats:p><jats:bold>Conclusions<\/jats:bold> This case report highlights that in an older child even longstanding extensive basidiobolomycosis can be safely treated with itraconazole. Surgery is not usually necessary in these patients.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2004.02419.x","type":"journal-article","created":{"date-parts":[[2005,6,28]],"date-time":"2005-06-28T17:27:13Z","timestamp":1119979633000},"page":"572-575","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Successful treatment of extensive basidiobolomycosis with oral itraconazole in a child"],"prefix":"10.1111","volume":"44","author":[{"given":"Renu","family":"Mathew","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Kumaravel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheela","family":"Kuruvilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renu G\u2019boy","family":"Varghese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Shashikala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Srinivasan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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