{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:06:01Z","timestamp":1791324361300,"version":"4.3.1"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2004,12,7]],"date-time":"2004-12-07T00:00:00Z","timestamp":1102377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2005,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Pemphigus is a rare and chronic life\u2010threatening disease. The clinical picture varies in reports from different regions of the world.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> To define the clinical forms of pemphigus in a large cohort of patients.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Prospective analysis of 1209 patients diagnosed and followed at the Pemphigus Research Unit, Tehran University for Medical Sciences, from 1984 to 2003.<\/jats:p><jats:p><jats:bold>Results\u2003\u2002<\/jats:bold> The mean age at onset was 42\u00a0years with a female to male ratio of 1.5\/1. The most frequent form was pemphigus vulgaris. In pemphigus vulgaris, patients\u2019 mucous membrane involvement alone was observed in 18%, skin involvement alone in 12%, and both in 70%. Pemphigus foliaceus was observed in 7% of the patients. Most complications were iatrogenic.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> In Iran, pemphigus vulgaris is the most frequent form of pemphigus. Females are more prone to the disease. The incidence of pemphigus in Tehran is approximately 1.6 per 100\u00a0000\/year, and in Iran 1.0 per 100\u00a0000\/year. The age of onset was lower than classically reported. Death occurred in 6.2% of the patients. In pemphigus vulgaris, the mucosal and skin form together had a worse prognosis than the other clinical forms.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2004.02501.x","type":"journal-article","created":{"date-parts":[[2006,8,22]],"date-time":"2006-08-22T09:25:21Z","timestamp":1156238721000},"page":"470-476","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":188,"title":["Pemphigus: Analysis of 1209 cases"],"prefix":"10.1111","volume":"44","author":[{"given":"Cheyda","family":"Chams\u2010Davatchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahin","family":"Valikhani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Daneshpazhooh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nafiseh","family":"Esmaili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamran","family":"Balighi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Hallaji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massoume","family":"Barzegari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Akhiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Ghodsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hosein","family":"Mortazavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Naraghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"558","volume-title":"Fitzpatrick's Dermatology in General Medicine","author":"Stanley JR","year":"2003"},{"key":"e_1_2_6_3_2","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1097\/00007611-200194070-00015","article-title":"Pemphigus in the southeastern United States","volume":"94","author":"Woldegiorgis S","year":"2001","journal-title":"South Med J"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2001.01247.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1993.tb02813.x"},{"key":"e_1_2_6_6_2","first-page":"9","article-title":"Tunisian pemphigus. 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