{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T12:44:03Z","timestamp":1792586643695,"version":"4.5.0"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,12,23]],"date-time":"2004-12-23T00:00:00Z","timestamp":1103760000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2006,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objective\u2002<\/jats:bold> To study the clinicoepidemiologic profile of cutaneous leishmaniasis (CL) in Yemen (Hajjah and adjacent regions) and to identify the <jats:italic>Leishmania<\/jats:italic> species responsible.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> All 136 cases [96 (70.6%) males and 40 (29.4%) females] were subjected to detailed analysis. The diagnosis was based on positive slit skin smear and histopathologic studies when needed. In four cases, <jats:italic>in vitro<\/jats:italic> culture and <jats:italic>Leishmania<\/jats:italic> characterization by isoenzyme electrophoresis of 15 isoenzymes were attempted.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Most of the patients (107; 78.7%) were residents of the Hajjah Governorate. The majority of the patients had a single noduloulcerative lesion on the face. Slit skin smear was positive for parasites in 128 (94%) cases (highly positive in 63 cases) and four <jats:italic>Leishmania<\/jats:italic> isolates were obtained. The isoenzyme characterization results revealed <jats:italic>L. tropica<\/jats:italic> to be the species responsible, and zymodeme analysis showed that one strain belonged to zymodeme MON137, and three strains belonged to two previously undescribed zymodemes similar to zymodeme MON71.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> CL seems to be endemic in this region. <jats:italic>L. tropica<\/jats:italic> was identified as the species responsible in four strains.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2004.02588.x","type":"journal-article","created":{"date-parts":[[2006,1,5]],"date-time":"2006-01-05T17:23:58Z","timestamp":1136481838000},"page":"40-45","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Cutaneous leishmaniasis in Yemen: clinicoepidemiologic features and a preliminary report on species identification"],"prefix":"10.1111","volume":"45","author":[{"given":"Mishri 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