{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T00:01:03Z","timestamp":1697328063591},"reference-count":19,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2005,1,21]],"date-time":"2005-01-21T00:00:00Z","timestamp":1106265600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2005,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Anti\u2010agalactosyl immunoglobulin G (IgG) antibodies (anti\u2010AG IgG) have been reported to be detected and correlated with disease activity in some collagen diseases.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> Forty\u2010seven serum samples from patients with localized scleroderma were examined using an enzyme\u2010linked immunosorbent assay.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Anti\u2010AG IgG were positive in 19% of patients with localized scleroderma. The frequency of anti\u2010AG IgG in generalized morphea was much higher than that in linear scleroderma or that in morphea. There was a significant correlation between anti\u2010AG IgG levels and the number of the sclerotic lesions and between anti\u2010AG IgG levels and the number of involved areas. The levels of anti\u2010AG IgG were significantly higher in patients with antinuclear antibody, antisingle\u2010stranded DNA antibody or rheumatoid factor than in those without.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Anti\u2010AG IgG can be an indicator of the severity of localized scleroderma.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2005.02584.x","type":"journal-article","created":{"date-parts":[[2005,10,3]],"date-time":"2005-10-03T08:22:55Z","timestamp":1128327775000},"page":"817-820","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Anti\u2010agalactosyl immunoglobulin G antibodies in localized 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