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Azelaic acid is a saturated dicarboxylic acid, which is naturally occurring and has been used in the treatment of rosacea, acne, and melasma. The 15% gel has a high efficacy and is generally well tolerated, with the local irritation (burning, stinging, itching, and scaling) being typically mild and transient. Azelaic acid 15% gel is considered effective and safe as a therapy for inflammatory papulo\u2010pustular rosacea and is suitable for use on all skin types.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2005.02769.x","type":"journal-article","created":{"date-parts":[[2007,3,29]],"date-time":"2007-03-29T11:05:39Z","timestamp":1175166339000},"page":"533-538","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Azelaic acid (15% gel) in the treatment of acne rosacea"],"prefix":"10.1111","volume":"46","author":[{"given":"Aditya K.","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa D.","family":"Gover","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,4,30]]},"reference":[{"key":"e_1_2_10_2_2","unstructured":"NDA Approvals for Calender Year 2002.http:\/\/www.fda.gov\/cder\/rdmt\/ndaaps02cy.htm. 10\u201014\u20102003."},{"key":"e_1_2_10_3_2","unstructured":"Intendis Inc.Finacea\u00ae (azelaic acid) Gel 15% (package insert) 2005."},{"key":"e_1_2_10_4_2","first-page":"545","volume-title":"SAE: Physicians\u2019 Desk Reference\u00ae","author":"Murray L.","year":"2003"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.308"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.11.1444"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/000155599750009906"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.3109\/09546639309082150"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70085-X"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1986.tb02856.x"},{"key":"e_1_2_10_11_2","first-page":"40","article-title":"Long\u2010term treatment of acne with 20% azelaic acid cream","volume":"143","author":"Cavicchini S","year":"1989","journal-title":"Acta Derm Venereol Suppl (Stockh)"},{"key":"e_1_2_10_12_2","first-page":"31","article-title":"Clinical and laboratory studies on treatment with 20% azelaic acid cream for acne","volume":"143","author":"Cunliffe WJ","year":"1989","journal-title":"Acta Derm Venereol Suppl (Stockh)"},{"key":"e_1_2_10_13_2","first-page":"538","article-title":"Comparison of combined azelaic acid cream plus oral minocycline with oral isotretinoin in severe acne","volume":"11","author":"Gollnick HP","year":"2001","journal-title":"Eur J Dermatol"},{"key":"e_1_2_10_14_2","first-page":"45","article-title":"Azelaic acid for the treatment of acne. 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