{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,24]],"date-time":"2023-12-24T20:29:35Z","timestamp":1703449775160},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,4,5]],"date-time":"2006-04-05T00:00:00Z","timestamp":1144195200000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Pustular eruptions of the extremities of the fingers and toes (acropustulosis) have been grouped under the single term \u201cHallopeau's acrodermatitis continua\u201d, which is a severe disease, with uninterrupted course, and successive eruptions that may become generalized. However, there is a form of acropustulosis with few lesions, evolving with remissions and relapses, with a benign course. It is necessary to separate these two forms of acropustulosis.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> I had the opportunity to observe six patients with a mitigated form of acropustulosis that does not fit into the diagnostic criteria of Hallopeau's acrodermatitis continua, which should be considered an independent clinical entity.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Sometimes, there is only one lesion in each eruption. The pustules are sterile and appear in small crops, located on the hyponychium or on the nail bed. The result is partial onycholysis or nail detachment. After each eruption there is complete recovery. Histopathology shows a nonspongiform pustule filled with neutrophils, with subcorneal localization. Four patients had follow\u2010up for at least 2\u00a0years, and one patient presented psoriasis lesions on the scalp after 11\u00a0years.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Acropustulosis as I described it can be differentiated from Halopeau's acrodermatitis continua using the following diagnostic criteria: (1) it is a benign condition; (2) the pustules are located on the hyponychium or nail bed; (3) pustules can be single or occur in small groups; (4) they reccur in flares, with restitutio ad integrum during the periods of remission; (5) the pustules are sterile; (6) microscopic study shows a subcorneal pustule (spongiform aspect is rare). A similar condition to that found in my cases was described by Radcliff\u2010Crocker (H. Radcliff\u2010Crocker, <jats:italic>Diseases of the Skin<\/jats:italic>, London: H.K. Lewis, 1888), termed \u201cdermatitis repens\u201d.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2006.02473.x","type":"journal-article","created":{"date-parts":[[2006,4,5]],"date-time":"2006-04-05T08:29:58Z","timestamp":1144225798000},"page":"389-393","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Acropustulosis repens"],"prefix":"10.1111","volume":"45","author":[{"given":"Nelson Guimar\u00e3es","family":"Proen\u00e7a","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,4,5]]},"reference":[{"key":"e_1_2_5_2_2","volume-title":"Diseases of the Skin","author":"Radcliff\u2010Crocker H","year":"1888"},{"key":"e_1_2_5_3_2","first-page":"420","article-title":"Sur une asphyxie locale des extr\u00e9mit\u00e9s avec polydactylite suppurative chronique et pouss\u00e9es \u00e9ph\u00e9m\u00e9res des dermatite pustuleuse diss\u00e9min\u00e9es et symm\u00e9triques","volume":"1","author":"Hallopeau H","year":"1890","journal-title":"Ann Dermatol Syphiligr"},{"key":"e_1_2_5_4_2","first-page":"473","article-title":"Sur les acrodermatites continues (polydactylites r\u00e9cidivantes)","volume":"8","author":"Hallopeau H","year":"1897","journal-title":"Ann Dermatol Syphilogr"},{"key":"e_1_2_5_5_2","first-page":"1633","volume-title":"Rook's Textbook of Dermatology","author":"Camp RD","year":"1998"},{"key":"e_1_2_5_6_2","first-page":"723","volume-title":"Fitzpatrick's Dermatology in General Medicine","author":"Christophers E","year":"1999"},{"key":"e_1_2_5_7_2","first-page":"256","article-title":"Pustulosis palmaris et plantaris with minimal lesions (type dermatite repens of Radcliff\u2010Crocker)","volume":"65","author":"Proen\u00e7a NG","year":"1990","journal-title":"An Bras Dermatol"},{"key":"e_1_2_5_8_2","first-page":"70","article-title":"Palmar and plantar pustulosis Radcliff\u2010Crocker's type, a variety of pustular psoriasis? (Letter)","volume":"70","author":"Proen\u00e7a NG","year":"1995","journal-title":"An Bras Dermatol"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1930.tb09379.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1930.tb09380.x"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/00015550260132488"},{"key":"e_1_2_5_12_2","doi-asserted-by":"crossref","first-page":"284","DOI":"10.2340\/0001555551284288","article-title":"Pustulosis palmaris et plantaris. Prevalence, clinical observations and prognosis","volume":"51","author":"Hellgren L","year":"1971","journal-title":"Acta Dermatol Venereol"},{"key":"e_1_2_5_13_2","first-page":"405","volume-title":"Psoriasis: Proceedings of the 2nd International Symposium.","author":"Karvonen J","year":"1977"},{"key":"e_1_2_5_14_2","first-page":"163","volume-title":"Psoriasis: Proceedings of the 2nd International Symposium.","author":"Zachariae H","year":"1977"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1978.tb02013.x"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(88)70088-2"},{"key":"e_1_2_5_17_2","first-page":"65","article-title":"Skeletal involvement in pustulosis palmo\u2010plantaris with special reference to the sterno\u2010costo\u2010clavicular joints","volume":"68","author":"Hradil E","year":"1988","journal-title":"Acta Dermatol Venereol"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.40.6.547"},{"key":"e_1_2_5_19_2","doi-asserted-by":"crossref","first-page":"289","DOI":"10.2340\/0001555551289294","article-title":"Pustulosis palmaris et plantaris. A follow\u2010up study of a ten\u2010year material","volume":"51","author":"Enfors W","year":"1971","journal-title":"Acta Dermatol Venereol"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1935.01470060002001"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-4632.2006.02473.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-4632.2006.02473.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:42:28Z","timestamp":1696898548000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-4632.2006.02473.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["10.1111\/j.1365-4632.2006.02473.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-4632.2006.02473.x","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4]]},"assertion":[{"value":"2006-04-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}