{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T14:39:20Z","timestamp":1779115160488,"version":"3.51.4"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,2,23]],"date-time":"2006-02-23T00:00:00Z","timestamp":1140652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2006,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Clinical and histopathological differential diagnosis is usually impossible in drug\u2010induced lichen planus (LP) and idiopathic LP. Naproxen is a nonsteroidal anti\u2010inflammatory drug, which is widely used for its analgesic, antipyretic and anti\u2010inflammatory effects. To the best of our knowledge, two case reports on naproxen\u2010induced LP have been reported.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Fifty\u2010five patients with LP, and a history of naproxen intake before their eruption, were investigated.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Twenty\u2010five patients (45.5%) had a history of naproxen intake prior to their eruption without any other medication. Twelve patients (21.8%) had a history of simultaneous use of naproxen with other drugs that were reported as inducers of LP. Eighteen patients (32.7%) had given a history of using naproxen together with drugs that had not been previously reported as inducers of LP. Moreover, in 42 patients, eruptive\u2010type LP development after naproxen intake, is an interesting observation. New lesions were not observed after the cessation of naproxen intake in any of the patients.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Naproxen might be accepted as an important inducer for LP, especially for the eruptive form.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2006.02670.x","type":"journal-article","created":{"date-parts":[[2006,2,23]],"date-time":"2006-02-23T09:31:17Z","timestamp":1140687077000},"page":"709-712","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Naproxen\u2010induced lichen planus: report of 55 cases"],"prefix":"10.1111","volume":"45","author":[{"given":"Ali Tahsin","family":"G\u00fcne\u0161","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emel","family":"Fetil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Turna","family":"\u0130lknur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bahar","family":"Birgin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u015eebnem","family":"\u00d6zkan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,2,23]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0738-081X(98)00004-2"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1159\/000248091"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(91)70241-S"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb01128.x"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(93)70176-T"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.114593"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(84)80236-4"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1080\/000155599750010823"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000247868"},{"key":"e_1_2_5_11_2","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1001\/jama.1978.03290110036005","article-title":"Spironolactone\u2010induced lichen planus","volume":"240","author":"Downham TF","year":"1978","journal-title":"JAMA"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1990.tb02122.x"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(89)90300-9"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(85)70110-7"},{"key":"e_1_2_5_15_2","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S1086-5802(16)30151-6","article-title":"Naproxen sodium","volume":"36","author":"Sutton LB","year":"1996","journal-title":"J Am Pharm Assoc (Wash)"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70025-3"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-4632.2006.02670.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-4632.2006.02670.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T01:58:16Z","timestamp":1696903096000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-4632.2006.02670.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2,23]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["10.1111\/j.1365-4632.2006.02670.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-4632.2006.02670.x","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2,23]]},"assertion":[{"value":"2006-02-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}