{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:46:17Z","timestamp":1790642777689,"version":"4.1.0"},"reference-count":62,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,9,22]],"date-time":"2006-09-22T00:00:00Z","timestamp":1158883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objective\u2002<\/jats:bold> To evaluate the epidemiology of pemphigus vulgaris (PV) in a Greek population and to compare it with other countries.<\/jats:p><jats:p><jats:bold>Materials and Methods\u2002<\/jats:bold> A retrospective study was conducted based on the records of 129\u00a0patients (41\u00a0males and 88\u00a0females) with PV who visited the Department of the Oral Medicine and Maxillofacial Pathology, Aristotle University of Thessaloniki, Greece and the State Hospital for Skin and Venereal Diseases of Thessaloniki, Greece, between 1985 and 2004. A group of 73\u00a0individuals was used as controls.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> The average annual incidence was found to be eight\u00a0patients per year. The male to female ratio was 1\u00a0:\u00a02.25. The difference in the age of onset between the two genders was statistically significant in marginal levels (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.05). In addition, 86.1% of the patients showed oral lesions only, 13.3% oral and skin lesions and 1.3% manifested oral, skin, and ocular lesions. Twenty\u2010eight of the 88\u00a0females were in the premenopausal period\u2010of\u2010life. Additionally, 19\u00a0males were farmers who had daily contact with organophosphoric pesticides. Co\u2010existing pathologic conditions were present in 75 of the 129\u00a0patients, and of these 75\u00a0patients six (8%) were diabetics, 15 (20%) presented with hypertension, two (2.6%) faced problems from their thyroid gland, and 10 (13.3%) of the patients complained of allergic reactions.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> The results of this study demonstrated a relatively high incidence of PV in northern Greece compared with that in other countries. The disease most frequently occured in the sixth decade\u2010of\u2010life and the majority of the patients manifested oral lesions. Further epidemiological studies are needed to elucidate whether this region is constituted from population groups with high susceptibility to PV.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2006.03044.x","type":"journal-article","created":{"date-parts":[[2006,9,22]],"date-time":"2006-09-22T13:16:12Z","timestamp":1158930972000},"page":"356-361","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Epidemiologic survey of pemphigus vulgaris with oral manifestations in northern Greece: Retrospective study of 129\u00a0patients"],"prefix":"10.1111","volume":"46","author":[{"given":"Evangelia Z.","family":"Michailidou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria A.","family":"Belazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasios 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