{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T03:44:57Z","timestamp":1794368697198,"version":"4.9.0"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,3,28]],"date-time":"2008-03-28T00:00:00Z","timestamp":1206662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2008,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Most treatment protocols for vitiligo usually do not result in complete repigmentation. Therefore, cosmetically acceptable camouflage, low cost and easy to handle alternatives are warranted.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> To evaluate the efficacy of low\u2010cost self\u2010tanner available in the Thai market in normal subjects with skin types III, IV, and V, and the efficacy for camouflage of 6% dihydroxyacetone (DHA) cream in the treatment of vitiligo on exposed areas of Asian skin.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> The study was divided into two parts. Part 1 is a prospective study of 15 healthy volunteers using three different DHA creams which were available in the Thai market with concentrations of 3.5%, 4.2%, and 5%. Part 2 was a retrospective study of 20 patients suffering from vitiligo affecting the face and\/or hands and feet who were treated with 6% DHA. The data were collected through direct examination, telephone interview, face\u2010to\u2010face interview, and photographs.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> In healthy volunteers, we found that color matching was achieved by using a higher concentration of DHA in darker\u2010skin subjects. Most of the vitiligo patients (88.9%) reported moderate to marked satisfaction with the cosmetic results of 6% DHA cream.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Dihydroxyacetone offers a safe and effective therapeutic option for recalcitrant vitiligo. Dark\u2010skin subjects need a higher concentration of DHA cream than lighter\u2010skin subjects.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2008.03356.x","type":"journal-article","created":{"date-parts":[[2008,3,29]],"date-time":"2008-03-29T11:14:35Z","timestamp":1206789275000},"page":"402-406","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Dihydroxyacetone: a safe camouflaging option in vitiligo"],"prefix":"10.1111","volume":"47","author":[{"given":"Natta","family":"Rajatanavin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suthida","family":"Suwanachote","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suthinee","family":"Kulkollakarn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,3,28]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000051757"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0781.2003.00003.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(96)90112-7"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(90)70028-G"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1978.01640210075025"},{"key":"e_1_2_6_7_2","first-page":"493","article-title":"Response to cosmetic disfigurement: patients with vitiligo","volume":"39","author":"Porter J","year":"1987","journal-title":"Cutis"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(86)70160-6"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000084751"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06456.x"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.12.1532"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1067\/S0190-9622(03)01484-1"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1961.137"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(05)70209-6"},{"key":"e_1_2_6_15_2","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/jid.1961.38","article-title":"Studies of some physical properties of the dihydroxyacetone color complex","volume":"36","author":"Goldman L","year":"1961","journal-title":"J Invest Dermatol"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.119670"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(92)70300-5"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2004.00118.x"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.140.7.886"},{"key":"e_1_2_6_20_2","first-page":"349","article-title":"Non\u2010carcinogenicity of dihydroxyacetone by skin painting","volume":"5","author":"Akin FJ","year":"1984","journal-title":"J Environ Pathol Toxicol Oncol"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2003.12.006"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-4632.2008.03356.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-4632.2008.03356.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T16:32:44Z","timestamp":1696869164000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-4632.2008.03356.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,28]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["10.1111\/j.1365-4632.2008.03356.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-4632.2008.03356.x","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,28]]},"assertion":[{"value":"2008-03-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}