{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T12:05:38Z","timestamp":1792152338489,"version":"4.4.0"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,4,14]],"date-time":"2008-04-14T00:00:00Z","timestamp":1208131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a case of an 18\u2010month\u2010old boy with slightly whitened fingernails and toenails since birth. At the age of 100 days, he progressively developed bilateral palmoplantar keratoderma which resulted in painful walking and disabled grasping. Perianal keratotic plaques and perioral hyperkeratotic erythema could also be observed. Both fingernails and toenails were dystrophic. Scalp hairs were sparse, but total alopecia was no present. The histopathologic changes of the biopsy from the inner side of the right foot showed nonspecific changes, which mainly showed highly hyperkeratosis and acanthosis with slight superficial perivascular inflammatory infiltration. A clinical diagnosis of Olmsted syndrome was established according to the typical feature of the lesions, which is the presence of symmetrical palmoplantar keratoderma with periorificial keratotic plaques. We review the literature and present a summary of all reported cases to date.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2008.03595.x","type":"journal-article","created":{"date-parts":[[2008,4,14]],"date-time":"2008-04-14T23:16:17Z","timestamp":1208214977000},"page":"432-437","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Olmsted syndrome: a case report and review of literature"],"prefix":"10.1111","volume":"47","author":[{"given":"Juan","family":"Tao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang\u2010zheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nian\u2010wen","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye\u2010qiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling\u2010yun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia\u2010wen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You\u2010wen","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya\u2010ting","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,4,14]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1927.04130170055008"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1995.01690180118028"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1990.tb08271.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(85)70141-7"},{"key":"e_1_2_5_6_2","first-page":"246","article-title":"Olmsted syndrome in an Iranian family: report of two new cases","volume":"10","author":"Yaghoobi R","year":"2007","journal-title":"Arch Iran Med"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2000.tb02229.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/11.11.1311"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.03.036"},{"key":"e_1_2_5_10_2","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1001\/archderm.1996.03890310083012","article-title":"Olmsted syndrome. Case report and identification of a keratin abnormality","volume":"132","author":"Kress DW","year":"1996","journal-title":"Arch Dermatol"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0560.2001.028005271.x"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200112000-00003"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1993.tb00404.x"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/120347540300700309"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2003.20410.x"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1991.tb06070.x"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(84)80264-9"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1997.01840.x"},{"key":"e_1_2_5_19_2","first-page":"394","article-title":"Olmsted syndrome. Successful therapy by treatment with etretinate","volume":"44","author":"Hausser I","year":"1993","journal-title":"Hautarzt"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1997.tb03097.x"},{"key":"e_1_2_5_21_2","first-page":"345","article-title":"Multiple epitheliomata cuniculata occurring in a mutilating keratoderma","volume":"35","author":"Barnett JH","year":"1985","journal-title":"Cutis"},{"key":"e_1_2_5_22_2","first-page":"933","article-title":"A case of Olmsted syndrome associated with a plantar verrucous carcinoma","volume":"109","author":"Yamamoto T","year":"1999","journal-title":"Jpn J Dermatol"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04453.x"},{"key":"e_1_2_5_24_2","first-page":"524","article-title":"Olmsted syndrome with squamous cell carcinoma of extremities and adenocarcinoma of the lung: failure to detect loricrin gene mutation","volume":"13","author":"Ogawa F","year":"2003","journal-title":"Eur J Dermatol"},{"key":"e_1_2_5_25_2","first-page":"708","article-title":"Olmsted\u2010Syndrom. Assoziation mit primar skelrosierender chiolangiitis und Immun\u2010schwache unklarer Genese","volume":"40","author":"Georgii A","year":"1989","journal-title":"Hautarzt"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.3329\/mmj.v16i1.262"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2005.01871.x"},{"key":"e_1_2_5_28_2","first-page":"603","article-title":"What syndrome is this? Olmsted syndrome","volume":"21","author":"Inamadar AC","year":"2004","journal-title":"Pediatr Dermatol"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2003.10.025"},{"key":"e_1_2_5_30_2","first-page":"538","article-title":"Olmsted syndrome","volume":"128","author":"Koch P","year":"2001","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_5_31_2","first-page":"52","article-title":"A case of Olmsted syndrome","volume":"36","author":"Pang XW","year":"2007","journal-title":"J Clin Dermatol"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-4632.2008.03595.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-4632.2008.03595.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T16:23:36Z","timestamp":1696868616000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-4632.2008.03595.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4,14]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1111\/j.1365-4632.2008.03595.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-4632.2008.03595.x","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4,14]]},"assertion":[{"value":"2008-04-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}