{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T20:43:48Z","timestamp":1792183428163,"version":"4.4.0"},"reference-count":65,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2011,7,22]],"date-time":"2011-07-22T00:00:00Z","timestamp":1311292800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Human T\u2010lymphotropic virus type 1 (HTLV\u20101) is a type C retrovirus primarily endemic to Japan, Central and South America, the Middle East, regions of Africa, and the Caribbean. Currently, an estimated 10\u201320 million people worldwide are infected with this virus. Although the majority of infected individuals remain asymptomatic, HTLV\u20101 is the causative agent of a number of disorders, notably adult T\u2010cell leukemia\/lymphoma (ATLL) and a progressive demyelinating neurological disorder, HTLV\u20101\u2010associated myelopathy\/tropical spastic paraparesis (HAM\/TSP). In addition to ATLL and HAM\/TSP, HTLV\u20101 has been associated with a spectrum of skin disorders, such as infective dermatitis associated with HTLV\u20101, crusted scabies, and leprosy. The understanding of the interaction between virus and host response has improved markedly, but there are still few treatment options.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2011.04882.x","type":"journal-article","created":{"date-parts":[[2011,7,24]],"date-time":"2011-07-24T13:48:49Z","timestamp":1311515329000},"page":"915-920","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Human T\u2010lymphotropic Virus 1 (HTLV\u20101) infection \u2013 dermatological implications"],"prefix":"10.1111","volume":"50","author":[{"given":"Masahiro","family":"Amano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuru","family":"Setoyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika","family":"Grant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco A.","family":"Kerdel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,7,22]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.77.12.7415"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.1993.9.381"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1086\/424598"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/13550289609146539"},{"key":"e_1_2_9_6_2","doi-asserted-by":"crossref","first-page":"4646","DOI":"10.1182\/blood.V88.12.4646.bloodjournal88124646","article-title":"Adult T\u2010cell leukemia\/lymphoma on a background of clonally expanding human T\u2010cell leukemia virus type\u2010I\u2010positive cells","volume":"88","author":"Cavrois M","year":"1996","journal-title":"Blood"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.3109\/13550289709015802"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.53.8.581"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02983553"},{"key":"e_1_2_9_10_2","first-page":"683","article-title":"Detection of HTLV\u2010I by polymerase chain reaction in situ hybridization in adult T\u2010cell leukemia\/lymphoma","volume":"152","author":"Setoyama M","year":"1998","journal-title":"Am J Pathol"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.19334-0"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1080115"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1086\/345364"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910510609"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(07)70081-6"},{"key":"e_1_2_9_16_2","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1182\/blood.V86.4.1444.bloodjournal8641444","article-title":"Human immature thymocytes as target cells of the leukemomogenic activity of human T\u2010cell leukemia virus type I","volume":"86","author":"Maguer\u2010Satta V","year":"1995","journal-title":"Blood"},{"key":"e_1_2_9_17_2","first-page":"1096","article-title":"The risk of development of HTLV\u2010I\u2010associated myelopathy\/tropical spastic paraparesis among persons infected with HTLV\u2010I","volume":"3","author":"Kaplan JE","year":"1990","journal-title":"J Acquir Immune Defic Syndr"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910430214"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2003.68.562"},{"key":"e_1_2_9_20_2","first-page":"100","article-title":"HTLV\u20101 associated infective dermatitis may be an indolent HTLV\u20101 associated lymphoma","volume":"4","author":"Goncalves DU","year":"2000","journal-title":"Braz J Infect Dis"},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)92413-V"},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-282X1992000200009"},{"key":"e_1_2_9_23_2","doi-asserted-by":"publisher","DOI":"10.1086\/367572"},{"key":"e_1_2_9_24_2","first-page":"73","volume-title":"Topics in Hematology","author":"Takatsuki K","year":"1977"},{"key":"e_1_2_9_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)90994-6"},{"key":"e_1_2_9_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1991.tb08051.x"},{"key":"e_1_2_9_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03165123"},{"key":"e_1_2_9_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(85)70161-2"},{"key":"e_1_2_9_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(93)90134-C"},{"key":"e_1_2_9_30_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1857968"},{"key":"e_1_2_9_31_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.8451645"},{"key":"e_1_2_9_32_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1999.39080904.x"},{"key":"e_1_2_9_33_2","first-page":"715","article-title":"Detection of human T\u2010lymphotropic virus (HTLV) tax sequences in New York city blood donors seronegative for HTLV types 1 and 2","volume":"10","author":"Dezzutti CS","year":"2003","journal-title":"Clin Diagn Lab Immunol"},{"key":"e_1_2_9_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12363010"},{"key":"e_1_2_9_35_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12371839"},{"key":"e_1_2_9_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1999.tb02093.x"},{"key":"e_1_2_9_37_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2008.00465.x"},{"key":"e_1_2_9_38_2","doi-asserted-by":"publisher","DOI":"10.1080\/02841860802657235"},{"key":"e_1_2_9_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2007.00456.x"},{"key":"e_1_2_9_40_2","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-0983"},{"key":"e_1_2_9_41_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1208979"},{"key":"e_1_2_9_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2400580"},{"key":"e_1_2_9_43_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20307"},{"key":"e_1_2_9_44_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2009.04008.x"},{"key":"e_1_2_9_45_2","doi-asserted-by":"publisher","DOI":"10.1086\/430064"},{"key":"e_1_2_9_46_2","first-page":"26","article-title":"Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV\u2010I","volume":"15","author":"Bittencourt AL","year":"2005","journal-title":"Eur J Dermatol"},{"key":"e_1_2_9_47_2","doi-asserted-by":"publisher","DOI":"10.1086\/508177"},{"key":"e_1_2_9_48_2","doi-asserted-by":"publisher","DOI":"10.1086\/432058"},{"key":"e_1_2_9_49_2","doi-asserted-by":"publisher","DOI":"10.1086\/524695"},{"key":"e_1_2_9_50_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2009005000008"},{"key":"e_1_2_9_51_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.4.439"},{"key":"e_1_2_9_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2004.04.006"},{"key":"e_1_2_9_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2006.07.003"},{"key":"e_1_2_9_54_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.164.5.2823"},{"key":"e_1_2_9_55_2","doi-asserted-by":"publisher","DOI":"10.1038\/341072a0"},{"key":"e_1_2_9_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)91793-5"},{"key":"e_1_2_9_57_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1995.tb01689.x"},{"key":"e_1_2_9_58_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880150108"},{"key":"e_1_2_9_59_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199111213252107"},{"key":"e_1_2_9_60_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880160207"},{"key":"e_1_2_9_61_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2005.72.855"},{"key":"e_1_2_9_62_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200206140-00015"},{"key":"e_1_2_9_63_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042560-199804010-00014"},{"key":"e_1_2_9_64_2","doi-asserted-by":"publisher","DOI":"10.1159\/000105445"},{"key":"e_1_2_9_65_2","doi-asserted-by":"crossref","first-page":"246","DOI":"10.4269\/ajtmh.2006.74.246","article-title":"Impairment of host immune response against Strongyloides stercoralis by human T cell lymphotropic virus type 1 infection","volume":"74","author":"Hirata T","year":"2006","journal-title":"Am J Trop Med Hyg"},{"key":"e_1_2_9_66_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1999.60.146"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-4632.2011.04882.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-4632.2011.04882.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T05:54:59Z","timestamp":1697349299000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-4632.2011.04882.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7,22]]},"references-count":65,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["10.1111\/j.1365-4632.2011.04882.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-4632.2011.04882.x","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7,22]]},"assertion":[{"value":"2011-07-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}