{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T10:15:54Z","timestamp":1784888154351,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,12,20]],"date-time":"2011-12-20T00:00:00Z","timestamp":1324339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Previous studies demonstrated clinical differences of early\u2010 and late\u2010onset psoriasis. However, epidemiological data and clinical characteristics of psoriasis occurring in geriatric patients have been rarely studied.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> Assessment of epidemiology and clinical features of psoriasis first occurring over the age of 60\u2003years, so\u2010called elderly\u2010onset psoriasis, based on clinical data.<\/jats:p><jats:p><jats:bold>Materials and methods\u2002<\/jats:bold> Among 4049 patients visiting our psoriasis clinic for the last 27\u2003years, patients were first divided into early\u2010 (onset age before 30\u2003years) and late\u2010onset psoriasis (onset age after 30\u2003years) based on our previous studies. Then, patients of late\u2010onset psoriasis were further divided into middle age\u2010onset group (onset age between 30 and 60\u2003years) and elderly\u2010onset group (onset age over 60\u2003years). Clinical characteristics of elderly\u2010onset psoriasis were compared with early\u2010 and middle age\u2010onset groups. We acquired the data both by physician\u2019s assessments and patients\u2019 responses.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Elderly\u2010onset patients comprised 3.2% of total patients, 129 out of 4049. They have shown a lower incidence of family history (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.05). The severity assessed by PASI score, body surface extent, and activity of individual lesions demonstrated that psoriasis of the elderly\u2010onset group was generally milder compared with early\u2010 and middle age\u2010onset groups (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.05). In clinical phenotypes, the proportion of guttate type and generalized pustular psoriasis type decreased remarkably, while that of erythroderma type increased (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.05)<jats:italic>.<\/jats:italic> There was a significant change in the body part of origin comparing early\u2010 and middle age\u2010onset groups (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.05). The proportion of scalp increased, while that of knee\u2013elbow and trunk decreased significantly (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.05). Patients\u2019 subjective sensation of disease course improved statistically comparing early\u2010 and middle age\u2010onset groups (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.05). There was no significant change in the degree of pruritus on psoriatic lesions and nail involvement (<jats:italic>P<\/jats:italic>\u2003&gt;\u20030.05).<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> The elderly\u2010onset group demonstrated milder disease courses and some changes in clinical phenotypes and body part of origin compared with early\u2010 and middle age\u2010onset groups. Therefore, it seems that patients whose onset of psoriasis was over the age of 60\u2003years might have distinct clinical features in some clinical aspects.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2011.04979.x","type":"journal-article","created":{"date-parts":[[2011,12,20]],"date-time":"2011-12-20T09:46:39Z","timestamp":1324374399000},"page":"53-58","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":74,"title":["Clinical study of psoriasis occurring over the age of 60\u2003years: is elderly\u2010onset psoriasis a distinct subtype?"],"prefix":"10.1111","volume":"51","author":[{"given":"Hyuck Hoon","family":"Kwon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In Ho","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jai Il","family":"Youn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,12,20]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1991.01680070084010"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1159\/000251595"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1999.tb02066.x"},{"key":"e_1_2_5_5_2","first-page":"1536","article-title":"Clinical study of 3123 psoriatic pateints","volume":"42","author":"Jo SJ","year":"2004","journal-title":"Korean J Dermatol"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.120470"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1586\/17469872.1.1.63"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(85)70188-0"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000247341"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1996.tb01537.x"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2000.00863.x"},{"key":"e_1_2_5_12_2","doi-asserted-by":"crossref","first-page":"155","DOI":"10.2340\/0001555552155160","article-title":"Climate therapy for Swedish psoriatics on Hvar, Yugoslavia","volume":"52","author":"Molin L","year":"1972","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_5_13_2","first-page":"7","article-title":"Psoriasis","volume":"53","author":"Molin L","year":"1973","journal-title":"Acta Derm Venerol"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12530762"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.2165\/00002512-200219110-00003"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1159\/000107628"},{"key":"e_1_2_5_17_2","first-page":"774","article-title":"Relationship of mild to severe psoriasis","volume":"13","author":"Farber EM","year":"1974","journal-title":"Cutis"},{"key":"e_1_2_5_18_2","volume-title":"Psoriasis: Influence of Sun and Seabathing in Psoriasis: Prevalence, Spontaneous Course and Genetics. 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