{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:58:43Z","timestamp":1762505923362},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,5,21]],"date-time":"2012-05-21T00:00:00Z","timestamp":1337558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Verrucous leprosy is rare, with only 18 cases reported in the literature. Visceral involvement is frequent but often overlooked, causing significant morbidity and mortality.<\/jats:p><jats:p><jats:bold>Case report\u2002<\/jats:bold> A 45\u2010year\u2010old Filipino male with a 16\u2010year history of hyperpigmented, hypoesthetic plaques, amputated digits, enlarged ulnar nerve, and cardiovascular congestion was diagnosed with Hansen\u2019s disease \u2013 lepromatous type. He had multiple cauliflower\u2010like nodules and plaques with foul\u2010smelling discharge on the lower extremities presenting a diagnostic dilemma. After an exhaustive search, the causative agent for these verrucous nodules was confirmed to still be <jats:italic>Mycobacterium leprae<\/jats:italic>. In addition, he had glomerulonephritis, hypertension, congestive heart failure, deep venous thrombosis, neuritis, keratitis, and glaucoma, which are all complications of advanced leprosy and multiple attacks of erythema nodosum leprosum reactions.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> He was treated with a multibacillary regimen of Rifampicin, Dapsone, Clofazimine, and systemic corticosteroids, with remarkable improvement.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2011.05219.x","type":"journal-article","created":{"date-parts":[[2012,5,21]],"date-time":"2012-05-21T09:57:08Z","timestamp":1337594228000},"page":"697-701","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Atypical Hansen\u2019s disease presenting as florid verrucous plaques on the lower extremities: a case report"],"prefix":"10.1111","volume":"51","author":[{"given":"Angela","family":"Yuchua\u2010Guillen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Belen L.","family":"Dofitas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,5,21]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"333","article-title":"Global Leprosy Situation 2009","volume":"84","year":"2009","journal-title":"Wkly Epidemiol Rec"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2000.00047-2.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"crossref","first-page":"20","DOI":"10.5070\/D32DJ7W0SX","article-title":"Elephantiasis nostras verrucosa on the legs and abdomen with morbid obesity in an Indian lady","volume":"14","author":"Sarma P","year":"2008","journal-title":"Dermatol Online J"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb05008.x"},{"key":"e_1_2_5_6_2","first-page":"92","article-title":"A study of dermatologic conditions in leprosy in\u2010patients","volume":"61","author":"Patki AH","year":"1989","journal-title":"Indian J Lepr"},{"key":"e_1_2_5_7_2","first-page":"183","article-title":"Hyperkeratotic and verrucous skin lesions on the lower extremities of leprosy patients","volume":"64","author":"Patki AH","year":"1992","journal-title":"Indian J Lepr"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2000.00860.x"},{"key":"e_1_2_5_9_2","first-page":"107","article-title":"Renal involvement in leprosy: retrospective analysis of 461 cases in Brazil","volume":"10","author":"da Silva GB","year":"2006","journal-title":"Braz J Infect Dis"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2001.25177"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02724408"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-4632.2011.05219.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-4632.2011.05219.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T21:58:05Z","timestamp":1697320685000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-4632.2011.05219.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,21]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1111\/j.1365-4632.2011.05219.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-4632.2011.05219.x","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,21]]},"assertion":[{"value":"2012-05-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}