{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T14:11:04Z","timestamp":1767967864414,"version":"3.49.0"},"reference-count":65,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,9,20]],"date-time":"2012-09-20T00:00:00Z","timestamp":1348099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Acne vulgaris is a common reason why adult women present to dermatologists and can be a clinical challenge to treat. It may also be an important sign of an underlying endocrine disease such as Polycystic Ovary Syndrome (PCOS). Although standard acne therapies can be successfully used to treat acne in adult female patients, hormonal treatment is a safe and effective therapeutic option that may provide an opportunity to better target acne in this population, even when other systemic therapies have failed. In this article, a practical approach to the adult female patient with acne will be reviewed to enhance the dermatologist\u2019s ability to use hormonal acne therapies and to better identify and evaluate patients with acne in the setting of a possible endocrine disorder.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2012.05519.x","type":"journal-article","created":{"date-parts":[[2012,9,21]],"date-time":"2012-09-21T01:55:23Z","timestamp":1348192523000},"page":"1162-1174","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Acne in the adult female patient: a practical approach"],"prefix":"10.1111","volume":"51","author":[{"given":"Faranak","family":"Kamangar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanade","family":"Shinkai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,9,20]]},"reference":[{"key":"e_1_2_16_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12541101"},{"key":"e_1_2_16_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp033487"},{"key":"e_1_2_16_4_2","first-page":"287","article-title":"Prevalence of acne vulgaris in Auckland senior high school students","volume":"108","author":"Lello J","year":"1995","journal-title":"N Z Med J"},{"key":"e_1_2_16_5_2","first-page":"94","article-title":"Acne vulgaris in the United States: a descriptive epidemiology","volume":"86","author":"Yentzer BA","year":"2010","journal-title":"Cutis"},{"key":"e_1_2_16_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)80056-5"},{"key":"e_1_2_16_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2001.00357.x"},{"key":"e_1_2_16_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.06.045"},{"key":"e_1_2_16_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.02979.x"},{"key":"e_1_2_16_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1997.d01-1144.x"},{"key":"e_1_2_16_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0738-081X(01)00209-7"},{"key":"e_1_2_16_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.4.454"},{"key":"e_1_2_16_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1972.01620150029011"},{"key":"e_1_2_16_14_2","first-page":"527","article-title":"Evaluating hyperandrogenism: a challenge in acne management","volume":"7","author":"Harper JC","year":"2008","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_16_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1994.01690030040006"},{"key":"e_1_2_16_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1991.01680020078009"},{"key":"e_1_2_16_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2004.03.010"},{"key":"e_1_2_16_18_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.76.2.524"},{"key":"e_1_2_16_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2009.08.008"},{"key":"e_1_2_16_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deq308"},{"key":"e_1_2_16_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2008.06.002"},{"key":"e_1_2_16_22_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.117382"},{"key":"e_1_2_16_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.140.4.423"},{"key":"e_1_2_16_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.11.021"},{"key":"e_1_2_16_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(97)70307-X"},{"key":"e_1_2_16_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.6.726"},{"key":"e_1_2_16_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61345-2"},{"key":"e_1_2_16_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)80064-3"},{"key":"e_1_2_16_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(15)30642-6"},{"key":"e_1_2_16_30_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.83.9.3078"},{"key":"e_1_2_16_31_2","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.84.11.6148"},{"key":"e_1_2_16_32_2","doi-asserted-by":"publisher","DOI":"10.1080\/gye.16.6.443.446"},{"key":"e_1_2_16_33_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.1998.00492.x"},{"key":"e_1_2_16_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2003.10.004"},{"key":"e_1_2_16_35_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra041536"},{"key":"e_1_2_16_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2006.00077.x"},{"key":"e_1_2_16_37_2","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200708040-00003"},{"key":"e_1_2_16_38_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016340903353284"},{"key":"e_1_2_16_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2004.05.007"},{"key":"e_1_2_16_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.02.014"},{"key":"e_1_2_16_41_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.86.2.517"},{"key":"e_1_2_16_42_2","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmq045"},{"key":"e_1_2_16_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.01.019"},{"key":"e_1_2_16_44_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.618"},{"key":"e_1_2_16_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2010.00657.x"},{"key":"e_1_2_16_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.11.1061"},{"key":"e_1_2_16_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2009.03.006"},{"key":"e_1_2_16_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.12.040"},{"key":"e_1_2_16_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2010.05.009"},{"key":"e_1_2_16_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13907-4"},{"key":"e_1_2_16_51_2","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S1701-2163(16)31016-7","article-title":"Absolute and attributable risk of venous thromboembolism in women on combined cyproterone acetate and ethinylestradiol","volume":"25","author":"Lidegaard O","year":"2003","journal-title":"J Obstet Gynaecol Can"},{"key":"e_1_2_16_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)90806-5"},{"key":"e_1_2_16_53_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/12.9.1851"},{"key":"e_1_2_16_54_2","first-page":"708","article-title":"A quantitative assessment of oral contraceptive use and risk of ovarian cancer","volume":"80","author":"Hankinson SE","year":"1992","journal-title":"Obstet Gynecol"},{"key":"e_1_2_16_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.12.002"},{"key":"e_1_2_16_56_2","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1001\/archderm.1994.01690030128027","article-title":"Frequency of pregnancy in acne patients taking oral antibiotics and oral contraceptives","volume":"130","author":"London BM","year":"1994","journal-title":"Arch Dermatol"},{"key":"e_1_2_16_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(97)80322-2"},{"key":"e_1_2_16_58_2","first-page":"CD000194","article-title":"Spironolactone versus placebo or in combination with steroids for hirsutism and\/or acne","author":"Brown J","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_16_59_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.105557"},{"key":"e_1_2_16_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.09.024"},{"key":"e_1_2_16_61_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10227-001-0152-4"},{"issue":"4","key":"e_1_2_16_62_2","first-page":"11","article-title":"Hormonal treatment of acne: review of current best evidence","volume":"8","author":"Tan J","year":"2004","journal-title":"J Cutan Med Surg"},{"key":"e_1_2_16_63_2","first-page":"2","article-title":"The effect of 2 combined oral contraceptives containing either drospirenone or cyproterone acetate on acne and seborrhea","volume":"69","author":"van Vloten WA","year":"2002","journal-title":"Cutis"},{"key":"e_1_2_16_64_2","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200607050-00002"},{"key":"e_1_2_16_65_2","unstructured":"MuraseJ.Fulfilling great expectations: caring for new mothers and mothers\u2010to beAmerican Academy of Dermatology 69th Annual Meeting. New Orleans LA 2011."},{"key":"e_1_2_16_66_2","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-199614020-00001"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-4632.2012.05519.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-4632.2012.05519.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T04:16:14Z","timestamp":1697343374000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-4632.2012.05519.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,20]]},"references-count":65,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1111\/j.1365-4632.2012.05519.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-4632.2012.05519.x","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,20]]},"assertion":[{"value":"2012-09-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}