{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:57:47Z","timestamp":1760043467105},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,12,26]],"date-time":"2012-12-26T00:00:00Z","timestamp":1356480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Human T\u2010cell lymphotropic virus type 1 (HTLV\u20101) is the etiologic agent of adult T\u2010cell leukemia\/lymphoma (ATLL), HTLV\u20101\u2010associated myelopathy\/tropical spastic paraparesis (HAM\/TSP), infective dermatitis associated with HTLV\u20101 (IDH), and various other clinical conditions. Several of these diseases can occur in association.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> Report an association of diseases related to HTLV\u20101 infection, occurring in an unusual age group.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Dermatological and laboratory exams were consecutively performed in HTLV\u20101\u2010infected individuals from January 2008 to July 2010 in the HTLV Outpatient Clinic at the Institute of Infectious Diseases \u201cEmilio Ribas\u201d in S\u00e3o Paulo, Brazil.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> A total of 193 individuals (73 HAM\/TSP and 120 asymptomatic carriers) were evaluated, three of which were associated with adult\u2010onset IDH and HAM\/TSP. In all three cases, the patients were affected by IDH after the development and progression of HAM\/TSP\u2010associated symptoms.<\/jats:p><jats:p><jats:bold>Limitations\u2002<\/jats:bold> Small number of cases because of the rarity of these diseases.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> We draw attention to the possibility of co\u2010presentation of adult\u2010onset IDH in patients with a previous diagnosis of HAM\/TSP, although IDH is a disease classically described in children. Thus, dermatologists should be aware of these diagnoses in areas endemic for HTLV\u20101 infection.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2012.05606.x","type":"journal-article","created":{"date-parts":[[2012,12,26]],"date-time":"2012-12-26T14:10:55Z","timestamp":1356531055000},"page":"63-68","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Co\u2010presentation of human T\u2010cell lymphotropic virus type 1 (HTLV\u20101)\u2010associated myelopathy\/tropical spastic paraparesis and adult\u2010onset infective dermatitis associated with HTLV\u20101 infection"],"prefix":"10.1111","volume":"52","author":[{"given":"Renata","family":"Okajima","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Casseb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 A.","family":"Sanches","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,12,26]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.79.6.2031"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)91298-5"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890380212"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042560-199600001-00009"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042560-199600001-00010"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.10.021"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042560-199600001-00006"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1086\/341251"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2000001200001"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1086\/590969"},{"key":"e_1_2_5_12_2","first-page":"1096","article-title":"The risk of development of HTLV\u2010I\u2010associated myelopathy\/tropical spastic paraparesis among persons infected with HTLV\u2010I","volume":"3","author":"Kaplan JE","year":"1990","journal-title":"J Acquir Immune Defic Syndr"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2005.05.010"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1086\/423942"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1966.tb12181.x"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1967.tb11479.x"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.4.439"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04568.x"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86822002000500013"},{"key":"e_1_2_5_20_2","first-page":"62","article-title":"Adult\u2010onset infective dermatitis associated with HTLV\u2010I. 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