{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T07:47:01Z","timestamp":1698738421108},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,1,24]],"date-time":"2013-01-24T00:00:00Z","timestamp":1358985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives\u2002<\/jats:bold> Netherton\u2019s syndrome (NS) is a rare autosomal recessive condition, first described in 1958, which involves a complex immunological dysfunction, ichthyosiform dermatitis, and erythroderma, characteristic defects of the hair shaft and atopy. Recurrent bacterial infection in the skin of patients with NS is frequent.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> This paper represents the first case report of leprosy and concurrent NS.<\/jats:p><jats:p><jats:bold>Discussion\u2002<\/jats:bold> This case merits discussion among doctors in endemic and non\u2010endemic areas to evaluate the chronic use of systemic corticosteroids as a risk factor for leprosy. The present patient came from an endemic area of leprosy and was treated chronically with systemic corticosteroids for erythroderma. This treatment, along with the immunodeficiency related to the syndrome and caused by a genetic mutation in <jats:italic>SPINK5<\/jats:italic>, may be a facilitating factor for the infection.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2012.05620.x","type":"journal-article","created":{"date-parts":[[2013,1,25]],"date-time":"2013-01-25T03:36:02Z","timestamp":1359084962000},"page":"186-190","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Netherton\u2019s syndrome and lepromatous leprosy: a mere coincidence?"],"prefix":"10.1111","volume":"52","author":[{"given":"Felipe Ladeira","family":"de Oliveira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruna Obeica","family":"Vasconcellos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thais Schiavo","family":"de Morais","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayara Brito","family":"Nascimento","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata","family":"Teles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Augusto","family":"da Costa Nery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos Jos\u00e9 Sumrell","family":"Miranda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luna","family":"Azulay\u2010Abulafia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,1,24]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1958.01560100059009"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(95)70159-1"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.7.875"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb04971.x"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2010.01522.x"},{"key":"e_1_2_4_7_2","first-page":"430","article-title":"Successful retinoid therapy of Netherton syndrome","volume":"40","author":"Hartschuh W","year":"1989","journal-title":"Hautarzt"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1994.tb00077.x"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc2374"},{"key":"e_1_2_4_10_2","first-page":"365","article-title":"Immunopathology of leprosy: the complexity of the mechanisms of host immune response to Mycobacterium leprae","volume":"35","author":"Goulart IM","year":"2002","journal-title":"Rev Soc Bras Med Trop"},{"key":"e_1_2_4_11_2","first-page":"747","article-title":"Significant absorption of topical tacrolimus in three patients with Netherton syndrome","volume":"137","author":"Allen A","year":"2001","journal-title":"Arch Dermatol"},{"key":"e_1_2_4_12_2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.2340\/0001555577203206","article-title":"Formation of active IL\u20101 beta from pro\u2010IL\u20101 beta catalyzed by stratum corneum chymotryptic enzyme in vitro","volume":"77","author":"Nylander\u2010Lundqvist E","year":"1997","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700284"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0022-202x.2001.01663.x"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(85)70170-3"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng1096"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature02326"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2004.11.006"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04625.x"},{"key":"e_1_2_4_20_2","doi-asserted-by":"publisher","DOI":"10.1086\/338625"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-4632.2012.05620.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-4632.2012.05620.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T05:26:22Z","timestamp":1698643582000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-4632.2012.05620.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,24]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["10.1111\/j.1365-4632.2012.05620.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-4632.2012.05620.x","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,24]]},"assertion":[{"value":"2013-01-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}