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Intermediate cutaneous leishmaniasis is distributed widely in <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>atin <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>merica and is characterized by cutaneous lesions, which may be accompanied by mucosal disease and demonstrate a tendency toward chronicity and relapse as well as resistance to standard treatment regimens. <jats:italic><jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>eishmania<\/jats:italic> parasites of the subgenus <jats:italic><jats:styled-content style=\"fixed-case\">V<\/jats:styled-content>iannia<\/jats:italic> have been identified as the major etiologic agent of this subset of infections. 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