{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T06:27:03Z","timestamp":1781504823002,"version":"3.54.1"},"reference-count":8,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,1,20]],"date-time":"2013-01-20T00:00:00Z","timestamp":1358640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2013,6]]},"abstract":"Abstract<\/jats:title>A case of rapidly relapsing pyoderma gangrenosum (PG<\/jats:styled-content>) of the left preauricular area with no undermined borders is described. This might be considered a case of malignant pyoderma (PM<\/jats:styled-content>), a rare variety of PG<\/jats:styled-content>. Five months after complete healing obtained with systemic corticosteroids, the preauricular lesion of PG<\/jats:styled-content> relapsed. As retreatment with oral methylprednisolone induced glucose intolerance and high arterial pressure, sulfa drugs were initially employed with a transitory recovery of the skin lesion. A successive prolonged course with minocycline induced a new complete resolution. To date, at six\u00a0months' follow\u2010up, the patient is relapse\u2010free. This case confirms that sulfa drugs and minocycline may also be considered alternative therapies in PM<\/jats:styled-content>. PM<\/jats:styled-content> is a variety of PG<\/jats:styled-content> characterized by specific morphological features, a higher tendency to relapse, and poor responsiveness to treatment.<\/jats:p>","DOI":"10.1111\/j.1365-4632.2012.05755.x","type":"journal-article","created":{"date-parts":[[2013,1,21]],"date-time":"2013-01-21T03:30:52Z","timestamp":1358739052000},"page":"753-756","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Treatment of a relapsing facial pyoderma gangrenosum (malignant pyoderma)"],"prefix":"10.1111","volume":"52","author":[{"given":"Lucia","family":"Mantovani","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine Section of Dermatology University of Ferrara Ferrara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Zauli","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine Section of Dermatology University of Ferrara Ferrara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oriele","family":"Sarno","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine Section of Dermatology University of Ferrara Ferrara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizia","family":"Querzoli","sequence":"additional","affiliation":[{"name":"Section of Anatomy Histology and Pathological Cytology University of Ferrara Ferrara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Corazza","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine Section of Dermatology University of Ferrara Ferrara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annarosa","family":"Virgili","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine Section of Dermatology University of Ferrara Ferrara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,20]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.2165\/11310730-000000000-00000"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2003.01919.x"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1996.tb00660.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1996.tb02981.x"},{"key":"e_1_2_4_6_1","first-page":"1008","article-title":"Pyoderma gangrenosum: an up date review","volume":"23","author":"Ruocco E","year":"2009","journal-title":"JEADV"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2009.00002"},{"key":"e_1_2_4_8_1","first-page":"369","article-title":"What do we know today about diaminodiaphenylsulfone?","volume":"53","author":"Golusin Z","year":"2000","journal-title":"Med Pregl"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-9877(90)90004-X"}],"container-title":["International Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-4632.2012.05755.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-4632.2012.05755.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T08:43:04Z","timestamp":1697359384000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-4632.2012.05755.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,20]]},"references-count":8,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["10.1111\/j.1365-4632.2012.05755.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-4632.2012.05755.x","archive":["Portico"],"relation":{},"ISSN":["0011-9059","1365-4632"],"issn-type":[{"value":"0011-9059","type":"print"},{"value":"1365-4632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,20]]},"assertion":[{"value":"2013-01-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}