{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T02:06:53Z","timestamp":1777860413009,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dermatology"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this study is to reveal demographic and clinical features of <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>eh\u00e7et's disease (<jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>) in a <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>urkish population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively evaluated the clinical findings of 521 patients with <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 521 patients (287 female and 234 male) were included in this study. Onset signs: oral ulceration (72.7%) was followed by genital ulceration (3.1%), ocular involvement (1.0%), and erythema nodosum\u2010like lesions (<jats:styled-content style=\"fixed-case\">ENLL<\/jats:styled-content>) (0.2%). In 120 patients (23%), the onset manifestation compromised more than one symptom. During follow\u2010up, in females and males respectively, oral ulceration was found in 100%, genital ulceration in 90.9% and in 82.5%, papulopustular lesions in 52.6% and in 71.4%, positive pathergy test in 45.3% and in 48.7%, <jats:styled-content style=\"fixed-case\">ENLL<\/jats:styled-content> in 43.6% and in 31.6%, ocular involvement in 36.9% and in 58.1%, gastrointestinal involvement in 6.6% and in 5.6%, joint involvement in 4.2% and in 6.4%, vascular involvement in 1.7% and in 10.6%, neurological involvement in 0% and in 4.7% and pulmonary involvement in 0.7% and in 0.7%. Genital ulceration and <jats:styled-content style=\"fixed-case\">ENLL<\/jats:styled-content> were found to be statistically higher in females than males. Papulopustular lesions and ocular, neurological, and vascular involvement were significantly higher in males than females.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In our study, systemic involvement was higher in males than females, as the disease is more severe in males than females. As the only initial finding of the disease can be genital ulceration or ocular manifestations, gynecologists, urologists, ophthalmologists, and family practitioners must keep in mind <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> as a differential diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1365-4632.2012.05756.x","type":"journal-article","created":{"date-parts":[[2013,8,23]],"date-time":"2013-08-23T03:38:58Z","timestamp":1377229138000},"page":"564-569","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Demographic and clinical features of 521 <scp>T<\/scp>urkish patients with <scp>B<\/scp>eh\u00e7et's disease"],"prefix":"10.1111","volume":"53","author":[{"given":"Ilknur","family":"Balta","sequence":"first","affiliation":[{"name":"Department of Dermatology Ministry of Health Etlik Ihtisas Training and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gulfer","family":"Akbay","sequence":"additional","affiliation":[{"name":"Department of Dermatology Ministry of Health Ankara Training and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goknur","family":"Kalkan","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine Gaziosmanpasa University Tokat Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meral","family":"Eksioglu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Ministry of Health Ankara Training and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,8,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.10.452"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2006.02921.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-008-0741-2"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-009-1127-9"},{"issue":"45","key":"e_1_2_6_6_1","first-page":"S58","article-title":"Beh\u00e7et's disease in Tunisia. 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