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Two clinical syndromes, the celery\u2010mugwort\u2010spice syndrome and the mugwort\u2010mustard\u2010allergy syndrome have been described in association with weed pollinosis. However, other associations between weed pollinosis and hypersensitivity to certain kinds of food have also been observed, like the mugwort\u2013peach, the ragweed\u2013melon\u2013banana, the plantain\u2013melon, the pellitory\u2013pistachio, the goosefoot\u2013fruit, the Russian thistle\u2013saffron, and the hop\u2013celery association. The number of allergen sources involved, the allergens, and influencing factors including geography, diet, and food preparation contribute to the high clinical complexity of PFS. So far, known causative cross\u2010reactive allergens include profilins, lipid transfer proteins, and high\u2010molecular weight allergens and\/or glycoallergens. The current usage of nonstandardized allergen extracts poses additional problems for both diagnosis and therapy of PFS patients. Further identification and characterization of involved allergens is inescapable for better understanding of PFS and vaccine development. Panels of recombinant allergens and\/or hypo\u2010allergens are promising tools to improve both PFS diagnostics and therapy.<\/jats:p>","DOI":"10.1111\/j.1398-9995.2006.00994.x","type":"journal-article","created":{"date-parts":[[2006,2,27]],"date-time":"2006-02-27T11:13:05Z","timestamp":1141038785000},"page":"461-476","source":"Crossref","is-referenced-by-count":191,"title":["Pollen\u2010food syndromes associated with weed pollinosis: an update from the molecular point of 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