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The two frequent clinical presentations of aspirin hypersensitivity are: aspirin\u2010induced bronchial asthma\/rhinosinusitis (AIA\/R) and aspirin\u2010induced urticaria\/angioedema (AIU). The decisive diagnosis is based on provocation tests with aspirin, as the <jats:italic>in vitro<\/jats:italic> test does not hold diagnostic value as yet. Detailed protocols of oral, bronchial and nasal aspirin provocation tests are presented. Indications, contraindications for the tests, the rules of drug withdrawal and equipment are reviewed. Patient supervision and interpretations of the tests are proposed.<\/jats:p>","DOI":"10.1111\/j.1398-9995.2007.01409.x","type":"journal-article","created":{"date-parts":[[2007,5,23]],"date-time":"2007-05-23T05:48:43Z","timestamp":1179899323000},"page":"1111-1118","source":"Crossref","is-referenced-by-count":316,"title":["EAACI\/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity"],"prefix":"10.1111","volume":"62","author":[{"given":"E.","family":"Ni\u017cankowska\u2010Mogilnicka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Bochenek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Mastalerz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"\u015awierczy\u0144ska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Picado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Scadding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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