{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T08:40:57Z","timestamp":1761986457229},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2010,6,24]],"date-time":"2010-06-24T00:00:00Z","timestamp":1277337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:sec><jats:label \/><jats:p> <jats:bold>To cite this article:<\/jats:bold> Patiwael JA, Jong NW, Burdorf A, Groot H, Gerth van Wijk R. Occupational allergy to bell pepper pollen in greenhouses in the Netherlands, an 8\u2010year follow\u2010up study. <jats:italic>Allergy<\/jats:italic> 2010; <jats:bold>65<\/jats:bold>: 1423\u20131429.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background:\u2002<\/jats:bold> Pollen from bell pepper plants cultivated in greenhouses are known to cause occupational allergic disease. A cross\u2010sectional study among 472 bell pepper employees in 1999 estimated prevalences for sensitization to bell pepper pollen of 28% and for work\u2010related allergic symptoms of 54%. There is scarce information on the incidence of work\u2010related allergy and its risk factors. Aims of the present study were to estimate the cumulative incidence of work\u2010related symptoms and sensitization to bell pepper pollen, and to determine risk factors for the onset of these symptoms and sensitization.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Bell pepper employees who participated in a cross\u2010sectional survey in 1999 were asked to take part in a follow\u2010up study in 2007. Information on demographic characteristics, job characteristics and allergic symptoms was gathered by means of a questionnaire. Furthermore, skin tests were performed with <jats:italic>a.o.<\/jats:italic> bell pepper pollen.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> In total, 280 of 472 employees were available for questionnaires and in 250 employees allergy tests were performed. During the 8\u2010year follow\u2010up, the cumulative incidence of sensitization to bell pepper pollen was 9% and of work\u2010related rhinitis 19%. Atopy [odds ratio (OR) 5.60] and smoking (OR 3.53) were significantly associated with development of rhinitis. The cumulative incidence of work\u2010related asthma symptoms was 8%. Again atopy (OR 5.03) and smoking (OR 11.85) were significant risk factors.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Cumulative incidences for sensitization to bell pepper pollen, work\u2010related rhinitis and asthma symptoms were 9%, 19% and 8%, respectively. 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