{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,10]],"date-time":"2023-11-10T15:40:28Z","timestamp":1699630828070},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,4,23]],"date-time":"2008-04-23T00:00:00Z","timestamp":1208908800000},"content-version":"vor","delay-in-days":9854,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Genetics"],"published-print":{"date-parts":[[1981,5]]},"abstract":"<jats:p>A 23\u2010year\u2010old phenotypic female with congenital heart disease, mental retardation and mild virilization was referred for evaluation of short stature and delayed sexual development. Endocrine studies revealed a markedly elevated serum testosterone, which was within the adult male range. At laparotomy, a small uterus, normal fallopian tubes and bilateral gonadal tumors, consisting of a left gonadoblastoma and right dysgerminoma were found. Trypsin G banding of peripheral blood revealed a 45, XO, 18p+ karyotype. Q banding demonstrated intense fluorescence of the distal portion of the extra material on chromosome 18, consistent with fluorescence of Y chromosomal heterochromatin. A combination of banding techniques enabled us to determine a 45, X, t(Y;18) (p11;p11) karyotype in peripheral blood. Cultures of gonadal tissue revealed 45, X, t(Y;18)\/46, XY mosaicism.<\/jats:p>","DOI":"10.1111\/j.1399-0004.1981.tb00717.x","type":"journal-article","created":{"date-parts":[[2010,7,18]],"date-time":"2010-07-18T23:25:23Z","timestamp":1279495523000},"page":"312-320","source":"Crossref","is-referenced-by-count":4,"title":["Cytogenetic and endocrine findings in a female with 45, X, t(Y;18) (p11;p11)"],"prefix":"10.1111","volume":"19","author":[{"given":"F. 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