{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T10:15:16Z","timestamp":1778926516774,"version":"3.51.4"},"reference-count":6,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,8,10]],"date-time":"2006-08-10T00:00:00Z","timestamp":1155168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Genetics"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:p>The people of Tumaco\u2010La Tolita culture inhabited the borders of present\u2010day Colombia and Ecuador. Already extinct by the time of the Spaniards arrival, they left a huge collection of pottery artifacts depicting everyday life; among these, disease representations were frequently crafted. In this article, we present the results of the personal examination of the largest collections of Tumaco\u2010La Tolita pottery in Colombia and Ecuador; cases of Down syndrome, achondroplasia, mucopolysaccharidosis I H, mucopolysaccharidosis IV, a tumor of the face and a benign tumor in an old woman were found. We believe these to be among the earliest artistic representations of disease.<\/jats:p>","DOI":"10.1111\/j.1399-0004.2006.00670.x","type":"journal-article","created":{"date-parts":[[2006,8,10]],"date-time":"2006-08-10T08:41:20Z","timestamp":1155199280000},"page":"188-191","source":"Crossref","is-referenced-by-count":25,"title":["Genetic and other diseases in the pottery of Tumaco\u2010La Tolita culture in Colombia\u2013Ecuador"],"prefix":"10.1111","volume":"70","author":[{"given":"JE","family":"Bernal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Briceno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,8,10]]},"reference":[{"issue":"262","key":"e_1_2_5_2_2","first-page":"219","article-title":"Estudio Esmeralde\u00f1os. Anales de la Universidad Central","volume":"39","author":"Uhle M","year":"1927","journal-title":"Quito"},{"key":"e_1_2_5_3_2","first-page":"13","volume-title":"Ministerio de Educaci\u00f3n","author":"Cubillos JC","year":"1955"},{"key":"e_1_2_5_4_2","first-page":"110","volume-title":"Ancient peoples and places","author":"Reichel\u2010Dolmatoff G","year":"1965"},{"key":"e_1_2_5_5_2","first-page":"134","article-title":"La Arqueolog\u00eda de Esmeraldas (Ecuador). Memorias de la misi\u00f3n Arqueol\u00f3gica Espa\u00f1ola en el Ecuador","author":"Alcina Franch J","year":"1979","journal-title":"Tomo I. Madrid: Ministerio Asuntos Exteriores"},{"key":"e_1_2_5_6_2","article-title":"The real earliest historical evidence of Down syndrome","volume":"132","author":"Mart\u00ednez\u2010Fr\u00edas Maria Luisa","year":"2005","journal-title":"Am J Med Genet"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-0004.2000.570504.x"}],"container-title":["Clinical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-0004.2006.00670.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-0004.2006.00670.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T23:44:43Z","timestamp":1696895083000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-0004.2006.00670.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8,10]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["10.1111\/j.1399-0004.2006.00670.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-0004.2006.00670.x","archive":["Portico"],"relation":{},"ISSN":["0009-9163","1399-0004"],"issn-type":[{"value":"0009-9163","type":"print"},{"value":"1399-0004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,8,10]]}}}