{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T22:55:04Z","timestamp":1773269704477,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,1,23]],"date-time":"2007-01-23T00:00:00Z","timestamp":1169510400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Genetics"],"published-print":{"date-parts":[[2007,2]]},"abstract":"<jats:p>This study compared language preferences to describe a cancer\u2010related mutation in three groups: 253 members of the general community, 20 clinicians working in cancer genetics, and 269 individuals at increased risk of carrying a cancer\u2010related mutation (including 198 women with a strong family history of breast and\/or ovarian cancer, and 71 individuals with a family history of hereditary non\u2010polyposis colorectal cancer). In the community sample, \u2018faulty gene\u2019 was the preferred term to describe a cancer\u2010related mutation, although females, those affected by cancer and those who felt cancer had a large impact on their lives were more likely to prefer the terms \u2018gene change\u2019 or \u2018altered gene\u2019. In contrast, the clinicians\u2019 preference ratings for \u2018faulty gene\u2019 and \u2018gene change\u2019 were equal. When forced to choose between \u2018faulty gene\u2019 and \u2018altered gene\u2019, the high\u2010risk patient group reported preferring \u2018faulty gene\u2019, although over 40% were happy with either term. Further research investigating individuals\u2019 understanding of the different terms that can be used to describe a cancer\u2010related mutation, and the functional impact of these terms on patients\u2019 thoughts and feelings about their condition and on their health\u2010related behavior after genetic counseling would be worthwhile.<\/jats:p>","DOI":"10.1111\/j.1399-0004.2007.00754.x","type":"journal-article","created":{"date-parts":[[2007,1,23]],"date-time":"2007-01-23T15:06:31Z","timestamp":1169564791000},"page":"140-147","source":"Crossref","is-referenced-by-count":3,"title":["A comparison of community, clinician, and patient preferences for naming a cancer\u2010related mutation"],"prefix":"10.1111","volume":"71","author":[{"given":"CE","family":"Wakefield","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Meiser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Homewood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Barlow\u2010Stewart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Tucker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,23]]},"reference":[{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/humu.10023"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/humu.10021"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.30264"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10897-005-5886-5"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/humu.10029"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.20113"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04334-8"},{"key":"e_1_2_10_9_2","article-title":"Development and pilot testing of two decision aids for individuals considering genetic testing for cancer risk","author":"Wakefield CE","journal-title":"J Genet Couns (manuscript number: JOGC-180"},{"key":"e_1_2_10_10_2","unstructured":"National Breast Cancer Centre.Current best advice about familial aspects of breast\/ovarian cancer. Sydney Australia:NHMRC National Breast Cancer Centre 2000."},{"key":"e_1_2_10_11_2","volume-title":"Familial aspects of bowel cancer: a guide for health professionals","author":"Australian Cancer Network","year":"2002"},{"key":"e_1_2_10_12_2","first-page":"303","volume-title":"The Centre for Genetics Education","author":"Barlow\u2010Stewart K","year":"2004"},{"key":"e_1_2_10_13_2","unstructured":"Barlow\u2010StewartK.Breast and ovarian cancer \u2013 genetic aspects. Accessed 27th June 2006 http:\/\/www.genetics.com.au."},{"key":"e_1_2_10_14_2","volume-title":"Australian Bureau of Statistics","author":"Australian Bureau of Statistics. 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