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To date, about 35 patients with cytogenetically visible deletions involving 4p15 and without Wolf\u2010Hirschhorn syndrome have been described, but the extent of the deletions has not been determined in the majority of these cases. The clinical manifestations of the patient described in this study were similar but not identical to the previously reported cases with 4p15 interstitial deletions. This finding indicates the presence of one or more genes involved in brain development and epilepsy in this chromosome region.<\/jats:p>","DOI":"10.1111\/j.1399-0004.2007.00901.x","type":"journal-article","created":{"date-parts":[[2010,7,19]],"date-time":"2010-07-19T12:03:29Z","timestamp":1279541009000},"page":"593-598","source":"Crossref","is-referenced-by-count":11,"title":["Interstitial deletion of chromosome 4p associated with mild mental retardation, epilepsy and polymicrogyria of the left temporal lobe"],"prefix":"10.1111","volume":"72","author":[{"given":"RS","family":"M\u00f8ller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CP","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GD","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Ullmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HH","family":"Ropers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Tommerup","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z","family":"T\u00fcmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,10,17]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(77)80642-2"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.21.3.223"},{"key":"e_1_2_6_4_2","first-page":"92","article-title":"Interstitial deletion of the band 4p15.3 defined by sequential replication banding","volume":"33","author":"Davies J","year":"1990","journal-title":"Ann Genet"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1985.tb00378.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1986.tb00518.x"},{"key":"e_1_2_6_7_2","first-page":"59","article-title":"Interstitial deletion of the short arm of chromosome 4. 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