{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T01:32:57Z","timestamp":1715995977129},"reference-count":58,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,11,2]],"date-time":"2011-11-02T00:00:00Z","timestamp":1320192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Genetics"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p>Gray SW, Hornik RC, Schwartz JS, Armstrong K. The impact of risk information exposure on women's beliefs about direct\u2010to\u2010consumer genetic testing for <jats:italic>BRCA<\/jats:italic> mutations.<\/jats:p><jats:p>Despite an increase in direct\u2010to\u2010consumer (DTC) genetic testing, little is known about how variations in website content might alter consumer behavior. We evaluated the impact of risk information provision on women's attitudes about DTC <jats:italic>BRCA<\/jats:italic> testing. We conducted a randomized experiment; women viewed a \u2018mock\u2019<jats:italic>BRCA<\/jats:italic> testing website without [control group (CG)] or with information on the potential risks of DTC testing [RG; framed two ways: unattributed risk (UR) information and risk information presented by experts (ER)]. Seven hundred and sixty\u2010seven women participated; mean age was 37 years, mean education was 15 years, and 79% of subjects were white. Women in the RG had less positive beliefs about DTC testing (mean RG = 23.8,CG = 25.2;p = 0.001), lower intentions to get tested (RG = 2.8,CG = 3.1;p = 0.03), were more likely to prefer clinic\u2010based testing (RG = 5.1,CG = 4.8;p = 0.03) and to report that they had seen enough risk information (RG = 5.3,CG = 4.7;p &lt; 0.001). UR and ER exposure produced similar effects. Effects did not differ for women with or without a personal\/family history of breast\/ovarian cancer. Exposing women to the potential risks of DTC <jats:italic>BRCA<\/jats:italic> testing altered their beliefs, preferences, and intentions. Risk messages appear to be salient to women irrespective of their chance of having a <jats:italic>BRCA<\/jats:italic> mutation.<\/jats:p>","DOI":"10.1111\/j.1399-0004.2011.01797.x","type":"journal-article","created":{"date-parts":[[2011,10,12]],"date-time":"2011-10-12T18:41:39Z","timestamp":1318444899000},"page":"29-37","source":"Crossref","is-referenced-by-count":12,"title":["The impact of risk information exposure on women's beliefs about direct\u2010to\u2010consumer genetic testing for <i>BRCA<\/i> mutations"],"prefix":"10.1111","volume":"81","author":[{"given":"SW","family":"Gray","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RC","family":"Hornik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JS","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,11,2]]},"reference":[{"key":"e_1_2_7_2_2","unstructured":"Genetics and Public Policy Center.Direct\u2010to\u2010consumer genetic testing companies2010 fromhttp:\/\/www.dnapolicy.org\/resources\/AlphabetizedDTCGeneticTestingCompanies.pdf. 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