{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T23:09:02Z","timestamp":1721257742391},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,12,13]],"date-time":"2011-12-13T00:00:00Z","timestamp":1323734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Genetics"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p>Voorwinden JS, Jaspers JPC, ter Beest JG, Kievit Y, Sijmons RH, Oosterwijk JC. The introduction of a choice to learn pre\u2010symptomatic DNA test results for <jats:italic>BRCA<\/jats:italic> or Lynch syndrome either face\u2010to\u2010face or by letter.<\/jats:p><jats:p>In predictive DNA testing for hereditary cancer, test results should traditionally be disclosed face\u2010to\u2010face. Increasingly, however, counselees ask to receive their test result at home by letter. To compare the quality of genetic counselling in the traditional way to a procedure in which counselees are offered a choice on how to get their test result. Counselees from families with a known <jats:italic>BRCA1\/2<\/jats:italic> or Lynch syndrome mutation were randomised into two groups. The control group was given the DNA test result in a face\u2010to\u2010face consultation. In the intervention group people could choose to learn their test result face\u2010to\u2010face or by letter. The quality of genetic counselling was assessed through questionnaires at three different moments. Data of 198 counselees were analysed. The quality of genetic counselling and psychological functioning were equally good in both groups. The majority of cases chose for disclosure by letter. The counselees with a good test result in the intervention group were the most satisfied. Our results indicate that in predictive DNA testing for <jats:italic>BRCA1\/2<\/jats:italic> and Lynch syndrome, a choice protocol is equally safe and more satisfying. Moreover, it is more efficient for both counsellor and counselee.<\/jats:p>","DOI":"10.1111\/j.1399-0004.2011.01811.x","type":"journal-article","created":{"date-parts":[[2011,11,17]],"date-time":"2011-11-17T17:57:57Z","timestamp":1321552677000},"page":"421-429","source":"Crossref","is-referenced-by-count":7,"title":["The introduction of a choice to learn pre\u2010symptomatic DNA test results for <i>BRCA<\/i> or Lynch syndrome either face\u2010to\u2010face or by letter"],"prefix":"10.1111","volume":"81","author":[{"given":"JS","family":"Voorwinden","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JPC","family":"Jaspers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JG","family":"ter Beest","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y","family":"Kievit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RH","family":"Sijmons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JC","family":"Oosterwijk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,12,13]]},"reference":[{"key":"e_1_2_7_2_2","unstructured":"Dutch Society of Clinical Genetics.Guideline predictive DNA\u2010testing.Quality commission of the VKGN.2007. 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The psychological impact of DNA testing is predicted by the counselees' perception, the medical impact by the pathogenic or uninformative BRCA1\/2\u2010result.","author":"Vos J","year":"2011","journal-title":"Psychooncology"},{"key":"e_1_2_7_24_2","doi-asserted-by":"crossref","first-page":"126","DOI":"10.5694\/j.1326-5377.2000.tb127938.x","article-title":"Psychological impact of genetic testing for adult\u2010onset disorders. 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