{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T07:41:02Z","timestamp":1697442062225},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,2,9]],"date-time":"2011-02-09T00:00:00Z","timestamp":1297209600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:p>Brice\u00f1o J, Ciria R, de la Mata M, Montero JL, Rufi\u00e1n S, L\u00f3pez\u2010Cillero P. Extended criteria donors in liver transplant candidates with hepatorenal syndrome.\u2028Clin Transplant 2011: 25: E257\u2013E263. \u00a9 2011 John Wiley &amp; Sons A\/S.<\/jats:p><jats:p><jats:bold>Abstract:\u2002<\/jats:bold> Hepatorenal syndrome (HRS) is a complication of cirrhosis with a poor prognosis without transplantation. The aim of this study is to analyze the influence of extended criteria donors (ECD) on the postoperative outcome of recipients with HRS. The last 498 patients were divided according to pre\u2010transplant type 1 or 2 HRS. Sixty\u2010six (13.25%) recipients fulfilled HRS criteria. Three\u2010month graft survival was 84% with at\u2010listing recipient serum creatinine ranging from 0\u20130.8\u2003mg\/dL; 80% with s\u2010creatinine\u2003=\u20030.9\u20131.5\u2003mg\/dL; 79% with s\u2010creatinine\u2003=\u20031.6\u20132.5\u2003mg\/dL; and 58% with s\u2010creatinine &gt;2.6\u2003mg\/dL (log\u2010rank\u2003=\u200318.039; p\u2003=\u20030.001). Recipients with HRS presented higher levels of pre\u2010transplant creatinine and lower levels of sodium, more episodes of hemodialysis and ascitis, and higher model of end\u2010stage liver disease\u2010scores. Three\u2010month graft survival in recipients with HRS relative to ECD\u2010variables showed differences in univariate analysis according to graft steatosis (85% in absent steatosis\u2003=\u20030\u201310%; 78% in mild steatosis\u2003=\u200310\u201330%; 76% in moderate steatosis\u2003=\u200330\u201360%; and 49% when severe steatosis &gt;60%; log\u2010rank\u2003=\u20035.146; p\u2003=\u20030.023). Cox\u2010proportional\u2010hazard\u2010model revealed that graft macrosteatosis per\u201030%\u2010increments (p\u2003=\u20030.000; HR\u2003=\u20031.303 [1.24\u20131.33] per\u201030%\u2010increment) and donors &gt;65\u2003yr (p\u2003=\u20030.089; HR\u2003=\u20031.622 [1.17\u20131.94]) were independent predictors of graft loss in recipients with HRS. In conclusion, the use of ECD in recipients with cirrhosis and HRS is a good option. However, grafts from moderate\u2010to\u2010severe steatosis and those from aged donors must be carefully allocated in candidates with HRS.<\/jats:p>","DOI":"10.1111\/j.1399-0012.2011.01402.x","type":"journal-article","created":{"date-parts":[[2011,2,9]],"date-time":"2011-02-09T12:17:01Z","timestamp":1297253821000},"source":"Crossref","is-referenced-by-count":2,"title":["Extended criteria donors in liver transplant candidates with hepatorenal syndrome"],"prefix":"10.1111","volume":"25","author":[{"given":"Javier","family":"Brice\u00f1o","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruben","family":"Ciria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"de la Mata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Luis","family":"Montero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebasti\u00e1n","family":"Rufi\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"L\u00f3pez\u2010Cillero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,2,9]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.33160"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20687"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.02086.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2008.03.007"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20017"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.trre.2007.03.006"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cld.2007.04.004"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.01758.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21668"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200208270-00015"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2003.50105"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000255319.07499.b7"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199707270-00012"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200105150-00007"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.24432"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510230122"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2007.02.001"},{"key":"e_1_2_5_19_2","first-page":"1310","article-title":"Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis","volume":"56","author":"Salerno F","year":"2007","journal-title":"Gut"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2007.08.004"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.22172"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.33993"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21566"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000244559.60989.5a"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2007.02.001"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-0012.2011.01402.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-0012.2011.01402.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T14:38:29Z","timestamp":1697380709000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-0012.2011.01402.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2,9]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["10.1111\/j.1399-0012.2011.01402.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-0012.2011.01402.x","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,2,9]]}}}