{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T07:16:59Z","timestamp":1715584619763},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,3,14]],"date-time":"2011-03-14T00:00:00Z","timestamp":1300060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:p>Ventura PA, Alharethi R, Budge D, Reid BB, Horne BD, Mason NO, Stoker S, Caine WT, Rasmusson B, Doty J, Clayson SE, Kfoury AG. Differential impact on post\u2010transplant outcomes between pulsatile\u2010 and continuous\u2010flow left ventricular assist devices.\u2028Clin Transplant 2011: 25: E390\u2013E395. \u00a9 2011 John Wiley &amp; Sons A\/S.<\/jats:p><jats:p><jats:bold>Abstract:\u2002<\/jats:bold><jats:bold> Background:\u2002<\/jats:bold> The HeartMate II (HMII) left ventricular assist device (LVAD) has proven reliable and durable and has become the preferred choice for bridge to transplant therapy (BTT) when compared with the pulsatile HeartMate XVE (XVE). In this study, we compared the post\u2010transplant (PTx) outcomes between XVE and HMII using a large national data registry.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> The Organ Procurement and Transplantation Network (OPTN)\/United Network for Organ Sharing (UNOS) Thoracic Registry database was queried for all patients implanted with either an XVE or an HMII as BTT during 2004\u20132009. Statistical analysis between XVE and HMII were performed using Kaplan\u2013Meier survival analysis and Cox regression analyses.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> A total of 673 patients were implanted with the XVE and 484 with HMII. When adjusted for age, gender, ethnicity, intra\u2010aortic balloon pump, ventilator, inotropes, dialysis, body mass index, creatinine, bilirubin, transfusion, pulmonary capillary wedge, and pulmonary arterial pressures, the HMII had similar one\u2010 and three\u2010yr survival (hazard ratio\u2003=\u20030.95, CI\u2003=\u20030.64, 1.42) and rejection\u2010free survival PTx compared to XVE. The XVE group had more early incidences of allograft rejection (AR) and hospitalization for infection (HI).<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Compared to XVE, patients with HMII have similar one\u2010 and three\u2010yr survival after heart transplantation with less risk of early graft rejection and significant infection. With a strong shift toward use of continuous\u2010flow LVADs, PTx outcomes are expected to continue to improve.<\/jats:p>","DOI":"10.1111\/j.1399-0012.2011.01433.x","type":"journal-article","created":{"date-parts":[[2011,3,15]],"date-time":"2011-03-15T02:02:44Z","timestamp":1300154564000},"source":"Crossref","is-referenced-by-count":13,"title":["Differential impact on post\u2010transplant outcomes between pulsatile\u2010 and continuous\u2010flow left ventricular assist devices"],"prefix":"10.1111","volume":"25","author":[{"given":"Pere A.","family":"Ventura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rami","family":"Alharethi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Budge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce B.","family":"Reid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin D.","family":"Horne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan O.","family":"Mason","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandi","family":"Stoker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William T.","family":"Caine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad","family":"Rasmusson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Doty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen E.","family":"Clayson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdallah G.","family":"Kfoury","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,3,14]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2001.118274"},{"key":"e_1_2_6_3_2","doi-asserted-by":"crossref","unstructured":"TayorDO StehlikJ EdwardsLBet\u00a0al.Registry of the International Society for Heart and Lung Transplantation: twenty\u2010sixth official adult heart transplant report\u20142009.J Heart Lung Transplant2009:28:1007.","DOI":"10.1016\/j.healun.2009.08.014"},{"key":"e_1_2_6_4_2","first-page":"9","article-title":"Second INTERMACS annual report: more than 1,000 primary left ventricular assist device implants","volume":"10","author":"Kirklin JK","year":"2009","journal-title":"J Heart Lung Transplant"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2003.07.035"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2008.02.087"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa067758"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.03.055"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2008.02.019"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.05.079"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.11.049"},{"key":"e_1_2_6_12_2","first-page":"31","article-title":"Prior human leukocyte antigen\u2010allosensitization and left ventricular assist device type affect degree of post\u2010implantation human leukocyte antigen\u2010allosensitization","volume":"4","author":"Drakos SG","year":"2009","journal-title":"J Heart Lung Transplant"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-0012.2011.01433.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-0012.2011.01433.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T13:26:05Z","timestamp":1697376365000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-0012.2011.01433.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,14]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["10.1111\/j.1399-0012.2011.01433.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-0012.2011.01433.x","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,14]]}}}