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Self\u2010reported non\u2010adherence to immune\u2010suppressant therapy in liver transplant recipients: demographic, interpersonal, and intrapersonal factors. \u2028Clin Transplant 2011 DOI: 10.1111\/j.1399\u20100012.2011.01489.x. \u2028\u00a9 2011 John Wiley &amp; Sons A\/S.<\/jats:p><jats:p><jats:bold>Abstract:\u2002<\/jats:bold> Adherence to immune suppressants and follow\u2010up care regimen is important in achieving optimal long\u2010term outcomes after organ transplantation. To identify patients most at risk for non\u2010adherence, this cross\u2010sectional, descriptive study explores the prevalence and correlates of non\u2010adherence to immune\u2010suppressant therapy among liver recipients. Anonymous questionnaires mailed consisted of the domains: (i) adherence barriers to immune suppressants, (ii) immune suppressants knowledge, (iii) demographics, (iv) social support, (v) medical co\u2010morbidities, and (vi) healthcare locus of control and other beliefs. Overall response was 49% (281\/572). Data analyzed for those transplanted within 10\u2003yr of study reveal 50% (119\/237) recipients or 9.2\/100 person years reporting non\u2010adherence. Non\u2010adherence was reported highest in the 2\u20135\u2003yr post\u2010transplant phase (69\/123, 56%). The highest immune\u2010suppressant non\u2010adherence rates were in recipients who are: divorced (26\/34, 76%, p\u2003=\u20030.0093), have a history of substance or alcohol use (42\/69, 61%, p\u2003=\u20030.0354), have mental health needs (50\/84, 60%, p\u2003=\u20030.0336), those who missed clinic appointments (25\/30, 83%, p\u2003&lt;\u20030.0001), and did not maintain medication logs (71\/122, 58%, p\u2003=\u20030.0168). Respondents who were non\u2010adherent with physician appointments were more than four and a half times as likely (OR 4.7, 95% CI 1.5\u201314.7, p\u2003=\u20030.008) to be non\u2010adherent with immune suppressants. In conclusion, half of our respondents report non\u2010adherence to immune suppressants. Factors identified may assist clinicians to gauge patients\u2019 non\u2010adherence risk and target resources.<\/jats:p>","DOI":"10.1111\/j.1399-0012.2011.01489.x","type":"journal-article","created":{"date-parts":[[2011,9,29]],"date-time":"2011-09-29T09:34:17Z","timestamp":1317288857000},"page":"328-335","source":"Crossref","is-referenced-by-count":49,"title":["Self\u2010reported non\u2010adherence to immune\u2010suppressant therapy in liver transplant recipients: demographic, interpersonal, and intrapersonal factors"],"prefix":"10.1111","volume":"26","author":[{"given":"Sangeeta","family":"Lamba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxanne","family":"Nagurka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunj K.","family":"Desai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaun J.","family":"Chun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart","family":"Holland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baburao","family":"Koneru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,9,29]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lts.2003.09.018"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000258599.65257.a6"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra050100"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20828"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.2165\/00019053-200422180-00006"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(02)02945-7"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20854"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.42.1.55"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200002150-00013"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510250526"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(03)00088-6"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840200117"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181ca87b0"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000129496.05898.02"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200201250-00017"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.2.6.757"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.02127.x"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.4037\/ajcc2007.16.3.222"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.01966.x"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pec.2004.09.003"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002800-200307000-00018"},{"key":"e_1_2_6_23_2","unstructured":"MedicalOutcomesStudy: SocialSupportSurvey. 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