{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:32:13Z","timestamp":1792276333847,"version":"4.4.0"},"reference-count":14,"publisher":"Wiley","issue":"s24","license":[{"start":{"date-parts":[[2012,6,29]],"date-time":"2012-06-29T00:00:00Z","timestamp":1340928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report the clinical and pathological findings of a case of <jats:italic>de novo<\/jats:italic> minimal change disease (<jats:styled-content style=\"fixed-case\">MCD<\/jats:styled-content>) after <jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>\u2010incompatible living kidney transplantation. A 62\u2010yr\u2010old man with end\u2010stage renal disease associated with type I diabetes received <jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content>\u2010incompatible kidney transplantation from his 58\u2010yr\u2010old wife. Although allograft function was excellent immediately after surgery, massive proteinuria (35\u00a0g\/d) appeared on post\u2010transplantation day 5. After the allograft biopsy taken on post\u2010transplantation day 6, he was treated with 12 cycles of plasma exchange, but the nephrotic\u2010range proteinuria showed no remission. The biopsy specimen showed no significant pathological findings on light microscopy, but electron microscopy showed diffuse effacement of podocyte foot processes. Based on the diagnosis of <jats:italic>de novo <\/jats:italic><jats:styled-content style=\"fixed-case\">MCD<\/jats:styled-content>, the patient received intravenous methylprednisolone pulse therapy, followed by high\u2010dose steroid maintenance therapy. The steroid therapy induced complete remission of nephrotic syndrome and stable allograft function immediately, which was also maintained at one yr after the transplantation.<\/jats:p>","DOI":"10.1111\/j.1399-0012.2012.01645.x","type":"journal-article","created":{"date-parts":[[2012,6,29]],"date-time":"2012-06-29T11:36:45Z","timestamp":1340969805000},"page":"81-85","source":"Crossref","is-referenced-by-count":4,"title":["<i>De novo<\/i> minimal change disease after <scp>ABO<\/scp>\u2010incompatible kidney transplantation"],"prefix":"10.1111","volume":"26","author":[{"given":"Yasushi","family":"Mochizuki","sequence":"first","affiliation":[{"name":"Department of Nephro\u2010Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahisa","family":"Iwata","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaharu","family":"Nishikido","sequence":"additional","affiliation":[{"name":"Division of Blood Purification Nagasaki University Hospital Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadashi","family":"Uramatsu","sequence":"additional","affiliation":[{"name":"Division of Blood Purification Nagasaki University Hospital Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Sakai","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Taguchi","sequence":"additional","affiliation":[{"name":"Department of Pathology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,6,29]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(96)00022-X"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199902270-00013"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.00655.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2005.00366.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.1998.v32.pm9740171"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198412000-00012"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1980.146"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-0012.2002.02023.x"},{"key":"e_1_2_4_10_1","first-page":"200","volume-title":"Heptinstall's Pathology of the Kidney","author":"Olson JL","year":"1998"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2005.00097.x"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000181385.68835.a0"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2005.00968.x"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199604043341402"},{"key":"e_1_2_4_15_1","first-page":"266","article-title":"Late de novo minimal change disease in a renal allograft","volume":"20","author":"Madhan KK","year":"2009","journal-title":"Saudi J Kidney Dis Transpl"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-0012.2012.01645.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-0012.2012.01645.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T16:47:03Z","timestamp":1694623623000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-0012.2012.01645.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,29]]},"references-count":14,"journal-issue":{"issue":"s24","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["10.1111\/j.1399-0012.2012.01645.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-0012.2012.01645.x","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,29]]}}}