{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T23:28:47Z","timestamp":1791156527069,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,7,4]],"date-time":"2006-07-04T00:00:00Z","timestamp":1151971200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:p>There is a paucity of information on food hypersensitivity (FHS) in young children and there are even fewer population\u2010based studies in this area. The aim of the study was to determine the prevalence of parentally reported FHS, and objectively diagnosed FHS amongst six\u2010year\u2010old children and to establish the rates of sensitization to key allergens. This population\u2010based cohort study recruited 798 6\u2010year\u2010olds resident on the Isle of Wight (UK). Sensitization rates, reported rates of FHS and objectively assessed FHS was established using food challenges. A total of 94 (11.8%) 6\u2003yr olds reported a problem with a food or food ingredient. The rate of sensitization to the pre\u2010defined panel of food allergens was 25\/700 (3.6%). Based on open food challenge and\/or suggestive history and skin tests, the prevalence of FHS was 2.5% (95% CI 1.5\u20133.8). Based on double\u2010blind challenges, a clinical diagnosis or suggestive history and positive skin tests, the prevalence was 1.6% (95% CI 0.9\u20132.7). The rates of perception of FHS are higher than the prevalence of sensitization to main food allergens and the prevalence of FHS based on food challenges. Milk, peanut and wheat were the key food allergens amongst those with positive challenges.<\/jats:p>","DOI":"10.1111\/j.1399-3038.2006.00428.x","type":"journal-article","created":{"date-parts":[[2006,7,6]],"date-time":"2006-07-06T14:25:42Z","timestamp":1152195942000},"page":"356-363","source":"Crossref","is-referenced-by-count":145,"title":["Prevalence of sensitization reported and objectively assessed food hypersensitivity amongst six\u2010year\u2010old children: A population\u2010based study"],"prefix":"10.1111","volume":"17","author":[{"given":"Carina","family":"Venter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Grundy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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