{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T06:24:24Z","timestamp":1773210264270,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,10,26]],"date-time":"2006-10-26T00:00:00Z","timestamp":1161820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2007,2]]},"abstract":"<jats:p>Young children sensitized with foods may develop early respiratory symptoms including nasal symptoms and cough, but not clinical manifestations in the skin or gastrointestinal tract. The long\u2010term outcome of these patients is largely unknown. We studied 36 children sensitized with cow's milk and three different age\u2010matched control groups. The patients were followed from 12 to 18\u2003months of age for at least 5\u2003yr with repeat skin testing and oral food challenge. After 2\u00bd\u2003yr, 63.9% (n\u2003=\u200323) of those in the mild allergy group lost sensitivity to foods; after 5\u2003yr, the number was 86.1% (n\u2003=\u200331). However, during the study period of 5\u2003yr, 69.4% (n\u2003=\u200325) simultaneously developed a sensitivity to common indoor airborne allergens. A similar trend was found only in the egg allergy control group. A positive family history and a history of parental smoking significantly increased the relative risk (RR) of sustaining nasal allergy symptoms (RR\u2003=\u20033.33 and 1.79, respectively). We concluded that allergy march from food sensitivity to sensitivity to airborne allergens may occur in a subset of children before 4\u2003yr of age. Genetics and environmental factors might independently contribute to the continuation of these respiratory symptoms.<\/jats:p>","DOI":"10.1111\/j.1399-3038.2006.00476.x","type":"journal-article","created":{"date-parts":[[2006,10,26]],"date-time":"2006-10-26T12:57:38Z","timestamp":1161867458000},"page":"81-85","source":"Crossref","is-referenced-by-count":16,"title":["Follow\u2010up of children with rhinitis and cough associated with milk allergy"],"prefix":"10.1111","volume":"18","author":[{"given":"Shih\u2010Wen","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,2,7]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3038.1999.101008.x"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)62258-2"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200001001-00013"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0905-6157.2003.00093.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(99)70393-3"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(86)80384-5"},{"key":"e_1_2_6_8_2","first-page":"379","article-title":"Food allergy: what link to respiratory symptoms","volume":"8","author":"James JM","year":"1997","journal-title":"J Respir Dis"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)90072-7"},{"key":"e_1_2_6_10_2","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1542\/peds.76.6.973","article-title":"Clinical manifestations of allergy related to breast\u2010 and cow's milk\u2010feeding","volume":"76","author":"Hyde DW","year":"1985","journal-title":"Pediatrics"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(88)90185-6"},{"key":"e_1_2_6_12_2","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1542\/peds.111.S3.1625","article-title":"Respiratory manifestations of food allergy","volume":"111","author":"James JM","year":"2003","journal-title":"Pediatrics"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.149.1.8111598"},{"key":"e_1_2_6_14_2","first-page":"127","article-title":"Is food allergy causing your patient's asthma symptoms","volume":"21","author":"Sicherer SH","year":"2000","journal-title":"J Respir Dis"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2005.00326.x"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(99)70300-3"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3038.2002.01045.x"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.111.S3.1631"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.116427"},{"key":"e_1_2_6_20_2","first-page":"314","article-title":"The growing genetic links and the early onset of atopic diseases in children stress the unique role of the atopic march: a meta\u2010analysis","volume":"9","author":"Cantani A","year":"1999","journal-title":"J Investig Allergol Clin Immunol"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.2000.00111.x"},{"key":"e_1_2_6_22_2","volume-title":"A Health Professional's Guide to Food Challenges","author":"Bock SA","year":"2004"}],"container-title":["Pediatric Allergy and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-3038.2006.00476.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-3038.2006.00476.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T09:00:27Z","timestamp":1697274027000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-3038.2006.00476.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,2]]}},"alternative-id":["10.1111\/j.1399-3038.2006.00476.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-3038.2006.00476.x","archive":["Portico"],"relation":{},"ISSN":["0905-6157","1399-3038"],"issn-type":[{"value":"0905-6157","type":"print"},{"value":"1399-3038","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,2]]}}}