{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T02:17:13Z","timestamp":1773109033188,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,3,7]],"date-time":"2007-03-07T00:00:00Z","timestamp":1173225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:p>Irritation of the skin of patients with atopic dermatitis by contact with rough fibres of synthetic or woollen clothes is well known. Therefore, it has been recommended that patients should wear cotton clothes. However, cotton also consists of rough fibres able to irritate the skin, whereas silk is characterized by smooth fibres without irritating potential. The aim of our study was to evaluate the clinical effect of Dermasilk<jats:sup>\u00ae<\/jats:sup>\u2013 a special silk fabric (sericin\u2010free silk treated with AEGIS AEM5772\/5 which has antibacterial properties) \u2013 in children with atopic dermatitis. A total of 22 children with mild\u2010to\u2010moderate atopic dermatitis were recruited for a study period of 3\u2003months. All of them received three different tube\u2010fabrics \u2013 Dermasilk, sericin\u2010free silk fabric without AEGIS AEM 5772\/5 and cotton, covering the cubital region. Patients were advised to wear the Dermasilk fabric all day long during the whole study period on one arm, whereas the sericin\u2010free AEGIS\u2010free silk tube had to be used during the first 2\u2003wk only on the other arm followed by the use of the cotton tube for the rest of the study period. Evaluation of the local SCORAD score was carried out at the beginning of the study, after 2, 4, 8 and 12\u2003wk. A significant reduction of the local SCORAD index of the Dermasilk covered arm was observed after 4, 8 and 12\u2003wk in comparison with the cotton\u2010covered arm score [median (quartile 1\u2013quartile 3)] 6.5 (5\u20138) vs. 8 (7\u20139), p\u2003&lt;\u20030.002; 6 (5.25\u20137.75) vs. 8 (7\u20139), p\u2003&lt;\u20030.0001; and 6 (5\u20136) vs. 8 (7.25\u201310), p\u2003&lt;\u20030.0001. The use of Dermasilk has a significant beneficial effect in atopic dermatitis because of the non\u2010irritating properties of silk as well as the antibacterial capacity of AEGIS AEM 5772\/5.<\/jats:p>","DOI":"10.1111\/j.1399-3038.2006.00511.x","type":"journal-article","created":{"date-parts":[[2007,3,7]],"date-time":"2007-03-07T18:07:04Z","timestamp":1173290824000},"page":"335-338","source":"Crossref","is-referenced-by-count":53,"title":["Action of a silk fabric treated with AEGIS<sup>TM<\/sup> in children with atopic dermatitis: A 3\u2010month trial"],"prefix":"10.1111","volume":"18","author":[{"given":"D. Y.","family":"Koller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Halmerbauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"B\u00f6ck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Engstler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,3,7]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(84)80008-1"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.1997.tb01236.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1974.tb06447.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12193-9"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.107.5.e80"},{"key":"e_1_2_6_7_2","first-page":"259","article-title":"A new durable antimicrobial finish for textiles","author":"Gettings RL","year":"1978","journal-title":"AATCC Book of Papers"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.2340\/00015555924447"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000247298"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.05705.x"},{"key":"e_1_2_6_11_2","first-page":"511","article-title":"Prevalence of occupational asthma in silk filatures","volume":"55","author":"Harindranath N","year":"1985","journal-title":"Ann Allergy"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000051627"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1373.2000.22507.x"}],"container-title":["Pediatric Allergy and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-3038.2006.00511.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-3038.2006.00511.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T08:12:44Z","timestamp":1696925564000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-3038.2006.00511.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3,7]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["10.1111\/j.1399-3038.2006.00511.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-3038.2006.00511.x","archive":["Portico"],"relation":{},"ISSN":["0905-6157","1399-3038"],"issn-type":[{"value":"0905-6157","type":"print"},{"value":"1399-3038","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,3,7]]}}}