{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T01:37:23Z","timestamp":1773884243434,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,10,14]],"date-time":"2005-10-14T00:00:00Z","timestamp":1129248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2005,12]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> To summarize the evolution of the pediatric liver transplant program in a developing country. Between April 1997, and September 2003, 32 cadaveric (CD) and 35 living donor (LD) liver transplantations were performed on 61 children (median age 3.8\u2003yr, range 0.5\u201316) at Ege University Organ Transplantation and Research Center. The patient's charts were reviewed retrospectively. The outcome of patient and graft survival was analyzed and the incidence of graft loss, complications and rejections was calculated. Indications for liver transplantation were metabolic liver disease (n\u2003=\u200317), biliary atresia (n\u2003=\u200314), viral hepatitis (n\u2003=\u20034), autoimmune hepatitis (n\u2003=\u20036), cryptogenic cirrhosis (n\u2003=\u200311), fulminant liver failure (n\u2003=\u20035) and others (n\u2003=\u20035). Seven of 61 children with chronic liver disease had hepatocellular carcinoma concomitantly. Median pediatric end\u2010stage liver disease score was 23 (range 1\u201354). Seven children (11.4%) were UNOS status I, 44 (72%) were UNOS status II and 10 (16.6%) were UNOS status III. The median follow\u2010up of the study population was 3.6\u2003yr (range 0.5\u20136). Actuarial patient survival rates at 1, 2, 3 and 4\u2003yr were 86, 86, 71.3 and 65% in the CD group vs. 80, 76, 67 and 67% in the LR group, respectively (p\u2003=\u2003NS). Patients listed as UNOS status 1 had lower survival rates than patients listed as UNOS status 2 and 3 (p\u2003&lt;\u20030.05). The mortality rate was 26.2%. Graft survival rates were 81, 81, 75 and 64% at 1, 2, 3 and 4\u2010yr respectively. Six patients (9%) underwent retransplantation. The main complications were infections (64.7%) and surgical complications (43.2%) (including biliary complication, vascular problems, postoperative bleeding, small for size and large for size). The incidence of acute cellular rejection was 39.3%, whereas chronic rejection was 7.4%. The result of liver transplantation in Turkish children was slightly inferior to those reported for North American and European children. However, an important characteristic of these patients that distinguishes them from Europe and North America is that most were UNOS status IIa and UNOS status I (44%). Despite technical and medical progress, infectious and biliary problems have continued to be an important cause of mortality in these patients.<\/jats:p>","DOI":"10.1111\/j.1399-3046.2005.00366.x","type":"journal-article","created":{"date-parts":[[2005,10,14]],"date-time":"2005-10-14T08:38:07Z","timestamp":1129279087000},"page":"723-728","source":"Crossref","is-referenced-by-count":19,"title":["Outcome of pediatric liver transplant recipients in Turkey: Single center experience"],"prefix":"10.1111","volume":"9","author":[{"given":"S.","family":"Aydogdu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Arikan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Kilic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Ozgenc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Akman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Unal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. V.","family":"Yagci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Tokat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,14]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(03)00150-0"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199809000-00014"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3046.2002.01082.x"},{"key":"e_1_2_7_5_2","first-page":"3620","article-title":"Living related liver transplantation:36 cases at the University of Hamburg","volume":"6","author":"Rogiers MX","year":"1994","journal-title":"Transplant Proc"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3046.2002.1r072.x"},{"key":"e_1_2_7_7_2","first-page":"251","article-title":"Validation of PELD severity score in a pediatric transplant candidate database","volume":"2","author":"Mazariegos GV","year":"2002","journal-title":"Am J Transpl"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200109000-00004"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2002.32941"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2002.33194"},{"key":"e_1_2_7_11_2","first-page":"554","volume-title":"Principles and Practice of Pediatric Infectious Diseases","author":"Green M","year":"2002"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3046.2003.00072.x"},{"key":"e_1_2_7_13_2","first-page":"3526","article-title":"Early postopertive infections in pediatric liver transplant recipients. 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