{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T13:12:12Z","timestamp":1791205932928,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"s7","license":[{"start":{"date-parts":[[2005,11,11]],"date-time":"2005-11-11T00:00:00Z","timestamp":1131667200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2005,12]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> Patients with Fanconi's Anemia (FA) have high rates of congenital physical abnormalities, bone marrow failure, leukemia, and solid tumors. Stem cell transplant (SCT) is often effective in curing bone marrow failure, but high\u2010risk patients, particularly those whose donor is not a human leukocyte antigen matched sibling, are vulnerable to early mortality from transplant\u2010related complications. Long\u2010term survivors of SCT have risks of solid tumors (particularly of the oral cavity), which are even higher than the already high \u2018baseline\u2019 risk of neoplasia in untransplanted FA patients. In this group, the major types of cancer are head and neck squamous cell carcinomas, and gynecologic malignancies. Rapid evaluation of new SCT preparative regimens would be useful in improving both short\u2010term and long\u2010term results.<\/jats:p>","DOI":"10.1111\/j.1399-3046.2005.00440.x","type":"journal-article","created":{"date-parts":[[2005,11,11]],"date-time":"2005-11-11T17:02:18Z","timestamp":1131728538000},"page":"81-86","source":"Crossref","is-referenced-by-count":35,"title":["Fanconi's Anemia, transplantation, and cancer"],"prefix":"10.1111","volume":"9","author":[{"given":"Blanche P","family":"Alter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,11,11]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11046"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-07-2170"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/35076590"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng1458"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-08-2915"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1073834"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(01)00173-3"},{"key":"e_1_2_5_9_2","first-page":"280","volume-title":"Nathan and Oski's Hematology of Infancy and Childhood","author":"Alter BP"},{"key":"e_1_2_5_10_2","first-page":"4064","article-title":"Association of complementation group and mutation type with clinical outcome in Fanconi Anemia","volume":"96","author":"Faivre L","year":"2000","journal-title":"Blood"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-01-0083"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-05-1498"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-04-1652"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20183"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-4608(99)00159-4"},{"key":"e_1_2_5_16_2","volume-title":"SEER Cancer Statistics Review, 1973\u20131998","author":"Ries LAG"},{"key":"e_1_2_5_17_2","volume-title":"Fanconi Anemia: Standards for Clinical Care","author":"Owen J","year":"2005"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011528310346"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1676-24442004000400011"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(01)00474-1"},{"key":"e_1_2_5_21_2","unstructured":"http:\/\/www.marrowfailure.cancer.gov."}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-3046.2005.00440.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-3046.2005.00440.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T15:27:28Z","timestamp":1695742048000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-3046.2005.00440.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11,11]]},"references-count":20,"journal-issue":{"issue":"s7","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["10.1111\/j.1399-3046.2005.00440.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-3046.2005.00440.x","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,11,11]]}}}