{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:14:28Z","timestamp":1791900868685,"version":"4.3.4"},"reference-count":55,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,5,17]],"date-time":"2006-05-17T00:00:00Z","timestamp":1147824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> For pediatric kidney transplant physicians, two aspects of Alport syndrome set the disease apart from other causes of terminal renal failure. First, an understanding of the genetics of Alport syndrome is needed to make appropriate decisions regarding potential related kidney donors to Alport patients requiring renal transplantation. Second, renal transplantation for Alport syndrome may be complicated by post\u2010transplant anti\u2010GBM nephritis, a problem that is nearly unique to this disease. This review discusses these aspects of Alport syndrome and attempts to provide rational recommendations for clinicians.<\/jats:p>","DOI":"10.1111\/j.1399-3046.2006.00528.x","type":"journal-article","created":{"date-parts":[[2006,5,17]],"date-time":"2006-05-17T08:46:22Z","timestamp":1147855582000},"page":"651-657","source":"Crossref","is-referenced-by-count":95,"title":["Renal transplantation in patients with Alport syndrome"],"prefix":"10.1111","volume":"10","author":[{"given":"Clifford E.","family":"Kashtan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,5,17]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1681\/ASN.V114649","article-title":"X\u2010linked Alport syndrome: natural history in 195 families and genotype\u2010phenotype correlations in males","volume":"11","author":"Jais JP","year":"2000","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00868709"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1999.00357.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1681\/ASN.V961023","article-title":"Ultrastructural and immunohistochemical findings in Alport's syndrome: a study of 108 patients from 97 Italian families with particular emphasis on COL4A5 gene mutation correlations","volume":"9","author":"Mazzucco G","year":"1998","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-200404000-00011"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000090034.71205.74"},{"key":"e_1_2_6_8_2","first-page":"267","article-title":"Renal prognosis in women with hereditary nephritis","volume":"23","author":"Grunfeld J\u2010P","year":"1985","journal-title":"Clin Nephrol"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1086\/302106"},{"key":"e_1_2_6_10_2","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1681\/ASN.V12197","article-title":"Structure of the human type IV collagen gene COL4A3 and mutations in autosomal Alport syndrome","volume":"12","author":"Heidet L","year":"2001","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2002.00379.x"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00780.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-005-2034-2"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1997.219"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1994.296"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2000.00358.x"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/16.10.2008"},{"key":"e_1_2_6_18_2","first-page":"1016","article-title":"Renal prognosis in Alport's and related syndromes: influence of the mode of inheritance","volume":"4","author":"Pochet JM","year":"1989","journal-title":"Nephrol Dial Transplant"},{"key":"e_1_2_6_19_2","volume-title":"GeneReviews at GeneTests: Medical Genetics Information Resource","author":"Kashtan CE","year":"1997"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfg393"},{"key":"e_1_2_6_21_2","first-page":"728","article-title":"Anti\u2010glomerular and anti\u2010tubular basement membrane nephritis in a renal allograft recipient with Alport's syndrome","volume":"118","author":"Diaz JI","year":"1994","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198812000-00013"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.1990.tb01898.x"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI112658"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1982.72"},{"key":"e_1_2_6_26_2","first-page":"35","article-title":"Renal transplantation in Alport's syndrome: anti\u2010glomerular basement membrane glomerulonephritis in the allograft","volume":"57","author":"Milliner DS","year":"1982","journal-title":"Mayo Clin Proc"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/6.11.893"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1159\/000168058"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1159\/000184294"},{"key":"e_1_2_6_30_2","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1007\/BF00850217","article-title":"The development of anti\u2010glomerular basement membrane nephritis in two children with Alport's syndrome after renal transplantation: characterization of the antibody target","volume":"3","author":"Van De Heuvel LPWJ","year":"1989","journal-title":"Pediatr Nephrol"},{"key":"e_1_2_6_31_2","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1159\/000418639","article-title":"Renal transplantation in Alport's syndrome: personal experience in twelve patients","volume":"80","author":"Berardinelli L","year":"1990","journal-title":"Contrib Nephrol"},{"key":"e_1_2_6_32_2","first-page":"299","article-title":"Kidney transplantation in Alport's syndrome: long\u2010term outcome and allograft anti\u2010GBM nephritis","volume":"38","author":"Gobel J","year":"1992","journal-title":"Clin Nephrol"},{"key":"e_1_2_6_33_2","first-page":"414","article-title":"Renal transplantation in Alport's syndrome","volume":"51","author":"Hayes DK","year":"1985","journal-title":"Am Surg"},{"key":"e_1_2_6_34_2","first-page":"77","article-title":"Inherited defects of renal basement membranes","volume":"18","author":"Noel LH","year":"1989","journal-title":"Adv Nephrol"},{"key":"e_1_2_6_35_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199111000-00013"},{"key":"e_1_2_6_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(80)80746-3"},{"key":"e_1_2_6_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)37714-7"},{"key":"e_1_2_6_38_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1998.00794.x"},{"key":"e_1_2_6_39_2","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1093\/oxfordjournals.ndt.a027085","article-title":"Identification of post\u2010transplant anti\u2010\u03b15(IV) collagen alloantibodies in X\u2010linked Alport syndrome","volume":"11","author":"Dehan P","year":"1996","journal-title":"Nephrol Dial Transplant"},{"key":"e_1_2_6_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1994.96"},{"key":"e_1_2_6_41_2","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1681\/ASN.V591714","article-title":"Autosomal recessive Alport syndrome: mutation in the COL4A3 gene in a woman with Alport syndrome and posttransplant antiglomerular basement membrane nephritis","volume":"5","author":"Ding J","year":"1995","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1995.170"},{"key":"e_1_2_6_43_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2005060670"},{"key":"e_1_2_6_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(98)90123-X"},{"key":"e_1_2_6_45_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1995.163"},{"key":"e_1_2_6_46_2","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1159\/000424811","article-title":"Immunohistologic findings in Alport syndrome","volume":"117","author":"Kashtan CE","year":"1996","journal-title":"Contrib Nephrol"},{"key":"e_1_2_6_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1994.413"},{"key":"e_1_2_6_48_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1989.244"},{"key":"e_1_2_6_49_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1996.316"},{"key":"e_1_2_6_50_2","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1681\/ASN.V52161","article-title":"COL4A5 deletions in three patients with Alport syndrome and posttransplant antiglomerular basement membrane nephritis","volume":"5","author":"Ding J","year":"1994","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_51_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-1004(1997)9:6<477::AID-HUMU1>3.0.CO;2-#"},{"key":"e_1_2_6_52_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117073"},{"key":"e_1_2_6_53_2","first-page":"508","article-title":"Posttransplant anti\u2010glomerular basement membrane nephritis in related Alport males with Alport syndrome","volume":"116","author":"Kashtan C","year":"1990","journal-title":"J Lab Clin Med"},{"key":"e_1_2_6_54_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200002270-00038"},{"key":"e_1_2_6_55_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.00428.x"},{"key":"e_1_2_6_56_2","first-page":"134","article-title":"Linear glomerular IgG fixation in renal allografts: incidence and significance in Alport syndrome","volume":"25","author":"Querin S","year":"1986","journal-title":"Clin Nephrol"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-3046.2006.00528.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-3046.2006.00528.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T17:00:15Z","timestamp":1696957215000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-3046.2006.00528.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5,17]]},"references-count":55,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["10.1111\/j.1399-3046.2006.00528.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-3046.2006.00528.x","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,5,17]]}}}