{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T23:50:12Z","timestamp":1767916212359,"version":"3.49.0"},"reference-count":7,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2007,10,28]],"date-time":"2007-10-28T00:00:00Z","timestamp":1193529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2007,12]]},"abstract":"<jats:p><jats:bold>Abstract:\u00a0<\/jats:bold> HSV causes serious complications in immunocompromised patients, especially SCT recipients. Although ACV is an effective antiviral prophylaxis, the emergence of ACV resistance is a growing problem. The authors describe two cases of fatal ACV\u2010resistant HSV in two pediatric patients following unrelated donor SCT. Despite the <jats:italic>in vitro<\/jats:italic> sensitivity of the HSV isolates to foscarnet, both patients failed to respond to foscarnet therapy. Other antiviral therapies should be considered in those patients who fail to show rapid clinical improvement.<\/jats:p>","DOI":"10.1111\/j.1399-3046.2007.00822.x","type":"journal-article","created":{"date-parts":[[2007,10,29]],"date-time":"2007-10-29T02:27:31Z","timestamp":1193624851000},"page":"942-944","source":"Crossref","is-referenced-by-count":27,"title":["Acyclovir\u2010resistant herpes simplex virus pneumonia post\u2010unrelated stem cell transplantation: A word of caution"],"prefix":"10.1111","volume":"11","author":[{"given":"Haydar","family":"Frangoul","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcia","family":"Wills","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Crossno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Engel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Domm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,10,28]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.287.6389.384"},{"key":"e_1_2_5_3_2","first-page":"584","volume-title":"Hemtopoietic Cell Transplantation","author":"Burns WH","year":"1999"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-97-6-813"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2004.03.002"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1701392"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1086\/315524"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1702591"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-3046.2007.00822.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-3046.2007.00822.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T22:10:47Z","timestamp":1696889447000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-3046.2007.00822.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10,28]]},"references-count":7,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["10.1111\/j.1399-3046.2007.00822.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-3046.2007.00822.x","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,10,28]]}}}